Posted on April 19, 2008 by E. Michael D. ("Mike") Scott
Based on a reanalysis of prostate cancer data from the Connecticut tumor registry, Albertsen writes in the World Journal of Urology that, “high risk prostate cancer is best identified by Gleason score 7-10.” However, he further concludes that there is no evidence to support the suggestion that “men with high-grade disease are less likely to [...]
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Posted on April 18, 2008 by E. Michael D. ("Mike") Scott
It appears that the American Society for Therapeutic Radiation Oncology (ASTRO)’s criteria for radiation failure may be significantly less rigorous than the criteria used by Walsh and his colleagues at Johns Hopkins (and by most other surgeons) to define surgical failure of treatment for localized prostate cancer.
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Posted on April 17, 2008 by E. Michael D. ("Mike") Scott
A second set of data have just been published from a major academic institution that show significant pre-surgical underestimation of Gleason scores (based on biopsy cores) compared to the postsurgical values (based on pathologic evaluation of the entire prostate). As with the data previously published by the University of Miami group, these data from Duke University show an improvement in the percentage [...]
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Posted on April 17, 2008 by E. Michael D. ("Mike") Scott
Two studies published in recent weeks provide interesting insights into the impact of treatment for localized prostate cancer on the men receiving treatment (and in one study their spouses/partners too).
Sanda et al. report data from over 1,200 men treated at a variety of major US institutions. In contrast, Namiki et al. compared the social impact and [...]
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Posted on April 17, 2008 by E. Michael D. ("Mike") Scott
In an article just published by Collin et al. in The Lancet Oncology a team of UK- and US-based authors state that early detection of prostate cancer through use of the PSA test in the USA is associated with a large decrease in prostate-cancer mortality compared to results from the UK in the period 1994 [...]
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Posted on April 16, 2008 by E. Michael D. ("Mike") Scott
Prostate cancer is a global epidemic. While some countries, such as Korea, seem relatively spared, the epidemic reaches across the seas. Given today’s web based technologies, we are positioned as never before to share information. The “New” Prostate Cancer InfoLink is one mechanism for sharing. As you will read below, there are others too.
This guest [...]
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Posted on April 15, 2008 by E. Michael D. ("Mike") Scott
We’ve come across a very well-considered article in an August 2007 issue of US News & World Report on the value and appropriateness of “new technology” in the treatment of prostate cancer that supports information you will find all over The “New” Prostate Cancer InfoLink. It’s always nice to know you’re not alone in your viewpoint!
Pass [...]
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Posted on April 14, 2008 by E. Michael D. ("Mike") Scott
We aren’t holding our breath. It’s amazing how many drugs are shown to do things in laboratory rats and mice but then have absolutely no effect whatsoever in larger animals — let alone humans. However, if you are interested in the concept that Lipitor and Celebrex in combination may be able to delay the progression [...]
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Posted on April 14, 2008 by E. Michael D. ("Mike") Scott
Researchers at Ohio State University in Columbus, Ohio are claiming that “high-field” MRIs are able to correctly identify localized prostate cancer (at least in 11 of 13 patients in a preliminary study) and also offer useful surgical road maps for case management. The findings are being presented at the annual meeting of the American Roentgen Ray Society in [...]
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Posted on April 13, 2008 by E. Michael D. ("Mike") Scott
The theoretical value of early adjuvant hormone therapy in prolonging survival is known. The practical value to the individual patient, when compared to the side effects and potential adverse consequences (including the cardiovascular adverse event mentioned in the immediately preceding blog post), remains open to considerable question, however.
A report in the Journal of Urology addresses data [...]
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