An opinion piece from today’s Boston Globe …

… is likely to stimulate some ferment among the prostate cancer advocacy community. (See the article
entitled “Does prostate screening make sense for you?“)

For the obsessively up-to-date reader …

… there are several new articles on research into clinical aspects of prostate cancer available on line from the UroToday International Journal.
This issue of UTIJ contains publications from the annual meeting of the Urological Research Society, which concluded on September 20th.  None of the articles appear to be of any great significance on their own, but taken as [...]

This morning’s news: Tuesday, September 30

More news of a relatively theoretical nature today:

The relevance of nuclear roundness variance in predicting risk of disease progression
Incorporation of the PCA3 gene marker into the PCPT risk calculator
Saving the neurovascular bundles has no impact on long-term continence

So maybe size really does matter!

It appears that urinary continence after radical prostatectomy (RP) may be associated with preoperative and postoperative membranous urethral length (MUL), percent change in MUL, and postoperative urethral, and periurethral fibrosis.

Your weekend prostate cancer news: Saturday, September 27

The news update for this weekend is largely of a “theoretical” as opposed to a “practical” nature. We have therefore kept the discussion brief and referred readers to the source material for more information.

What are the right eligibility criteria for active surveillance?

A couple of days ago we mentioned an abstract of a paper we had seen by Suardi et al. that discussed the “misclassification” of patients as being appropriate for active surveillence (AS). We have now had the chance to read this entire paper and are clearer about this analysis.

Vitamin D deficiency and prostate cancer management

Many prostate cancer patients use vitamin D supplements as a way to assist prevention of bone matrix deterioration, to prevent the potential for bone fractures, and simply to ensure avoidance of vitamin D deficiency.
Tangpricha has recently updated his chapter on vitamin D deficiency and related disorders on eMedicine, and this review may be of interest to [...]

Another serious side effect of bisphosphonates reported

According to HealthDay, a letter to the editor published today in the New England Journal of Medicine reports the very rare occurrence of inflammatory eye disease in patients being treated with bisphosphonates, e.g., alendronate (Fosamax), pamidronate (Aredia), zoledronic acid (Zometa), and others.

Non-ASTRO-related news update: Thursday, September 25

Additional, non-ASTRO-related news today  includes the following:

Screening, treatment, and mortality in Medicare-eligible populations
Genetic variants and relationships to clinical and pathological variables
The application of MRI in prostate cancer management
Predictors of aggressive biochemical recurrence after radical prostatectomy

ASTRO prostate cancer reports: no. 3

Prostate cancer reports from the 50th annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), held in Boston, have kindly been provided by Eyad Abu-Isa, MD, a resident in radiation oncology at the University of Michigan
This year’s scientific sessions concluded on Wednesday with two sessions focused on prostate cancer therapies and long-term outcomes and one afternoon session focused [...]