An article by Ma et al., pre-published on line in Lancet Oncology, has further established the risks associating obesity, diabetes, and death from prostate cancer. An excellent summary of the findings has been published on MedPage Today, and we refer readers to that article for more information, but the core findings of the of the study are that:
- Compared with men who had a body mass index (BMI) < 25, overweight men (BMI 25- 30) had a prostate cancer mortality hazard ratio of 1.47, and obesity (BMI > 30) increased the hazard ratio to 2.66
- Men with the highest 25 percent of C-peptide concentrations had a more than twofold greater risk of prostate mortality compared with men in the lowest 25 percent
- Men who were overweight or obese and had high C-peptide concentrations were more than four times more likely to die of prostate cancer compared to normal-weight men with low C-peptide concentrations
This study, based on an analysis of data from > 2,500 prostate cancer cases, included 989 men who were overweight and 87 who were obese. It seems we are likely to hear a great deal more about the relationships between metabolic syndrome and prostate cancer risk in the future.
In the meantime … Get some of that weight off guys! It just ain’t good for you!
Filed under: Management, Prevention, Treatment | Tagged: obesity insulin risk
