We have separately addressed the publication of data from the Cleveland Clinic on outcomes in men with Gleason scores of 3 + 4 compared to 4 + 3. Other reports today cover:
- Potential to improve the prognostic accuracy of the PCPT-based Prostate Cancer Risk Calculator
- Lack of impact of body mass index on outcome following radical prostatectomy in a German cohort
Hernandez et al. have conducted a complicated analysis of prognostic information provided by the Prostate Cancer Risk Calculator and compared it to prognostic information provided by PSA alone. They conclude that the addition of free PSA data and number of positive biopsy cores to the information currently required by the Prostate Cancer Risk calculator would improve the accuracy of this predictive tool.
Pfitzenmaier et al. have analyzed data from 620 men treated by radical prostatectomy in Heidelberg, Germany to evaluate the effect of body mass index (BMI) on the histopathological and clinical outcome in prostate cancer. Patients were categorized as “normal weight,” “overweight,” or “obese” according to standard BMI classifications. They conclude that in this mid-European study population, BMI could not be shown to be a predictor of adverse prognosis either for histopathological features or for clinical outcome (e.g., biochemical relapse-free, prostate cancer-specific, and overall survival) after radical prostatectomy.
Filed under: Diagnosis, Management, Treatment Tagged: | accuracy, BMI, prognosis, risk
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