Alcohol consumption and prostate cancer

Historically, literature reviews have come to the conclusion that there is no association between alcohol use and prostate cancer incidence. However, …

Race, socioeconomic status, and prostate cancer

The issue of whether race and socioeconomic status impact prostate cancer treatment outcomes is fraught with all sorts of pitfalls: emotional, statistical, political, medical, societal, you name it.

The Thursday prostate cancer news: February 12, 2009

Four new reports today deal with: Higher grade disease in men diagnosed with prostate cancer because of LUTS The role of MR/MRI in prostate biopsy for carefully defined patients Risk for understaging of prostate cancer Sorenafib in treatment of patients with castration-resistant prostate cancer

Can CTC counts be used as surrogate endpoints in clinical trials?

Intermediate or surrogate endpoints for survival can shorten timelines for drug approval. A paper just published on line in Lancet Oncology aimed to assess the value of circulating tumor cell (CTC) counts as a prognostic factor for survival.

New NCCN prostate cancer management guidelines issued

The 2009 version of the National Comprehensive Cancer Network’s guidelines for treatment of prostate cancer are now available online.

Sarcosine levels: a possible new test for aggressive prostate cancer?

According to a report from the BBC today, a Letter to the Editor just published in the journal Nature links a group of small molecules produced in men with prostate cancer (and particularly a metabolite known as sarcosine) to more aggressive forms of the disease.

Wednesday’s prostate cancer news: February 11, 2009

Today’s news reports contain four key items: A review of the potential of phytochemicals in treatment of prostate cancer A Norwegian study on correlation between biopsy-based and post-surgical Gleason scores A retrospective study on risk for prostate cancer in men being treated with testosterone replacement therapy An announcement of new data on PSP94 in the [...]

Nerve grafting after non-nerve-sparing RP

The use of  nerve grafting as a procedure to  preserve erectile function in men who require neurovascular bundle resection for cancer control has long been controversial, and results over the years have been varied.

The latest epistle from Dana Jennings …

… is entitled “Love in the Time of Prostate Cancer” and appeared in the New York Times Health blog yesterday. Enjoy!

Cougar Biotech and FDA agree on new abiraterone trial

According to MarketWatch, Cougar Biotechnology has announced agreement with the US Food & Drug Administration regarding the structure of another Phase III trial of abiraterone acetate in prostate cancer.

If you are a US citizen, it’s time to …

… call your Senators and your Congress(wo)men. Why? Go read the opinion piece by actor Patrick Swayze that appears in today’s Washington Post and that has also been posted on The “New Prostate Cancer InfoLink Social Network. That’s why. Don’t just sit on the sidelines. Take action … NOW.

Prostate cancer awareness — the poll results

Surprisingly only 15 readers felt motivated to vote last week on the relevance of Prostate Cancer Awareness Week compared to other potential initiatives — 8/15 (53 percent) favored continuation of the current PCAW initiative compared to others, but perhaps the most telling fact is that such a small number of readers felt motivated to vote [...]

Supplements and prostate cancer prevention: an update

An article by Collins on the CalorieLab web site offers a sound summary of “where we are” (or perhaps more accurately “where we aren’t”) with regard to the use of supplements in the prevention of prostate cancer.

The weekend prostate cancer news: February 7, 2009

After yesterday’s glut of interesting new publications, we have only one significant new report today — a review article on the potential of so-called Src inhibitors in the management of metastatic, hormone-refractory disease.

Re-biopsy of patients with an initial diagnosis of high-grade PIN

With the increasing use of initial 12-core biopsy templates, there is a question about the interpretation of the amount of high-grade prostatic intraepithelial neoplasia (HGPIN) found on initial biopsy and risk for prostate cancer.

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