AUA report and update no. 11: Thursday, April 30, 2009

Klotz et al. (abstract no. 1682) presented data on Tuesday updating information about their 14-year-long series of patients managed with active surveillance.

AUA report and update no. 10: Thursday, April 30, 2009

In a plenary session on Tuesday, Dr. William Aronson summarized current understanding about the impact of diet and lifestyle on prostate cancer development and progression.

Over 380,000 new cases a year in 2030?

A paper just published in the Journal of Clinical Oncology ( and available in full on line) includes data projecting 382,000 new cases of prostate cancer in the USA in 2030.

Gen-Probe to initiate Phase III trial of PCA3 test in USA

The prostate cancer gene 3 or PCA3 test has been available for some time under research protocols in the USA. This means that while the test has been accessible at a cost, it has not been available as a standard commercial test (in the same way as a PSA test is). Today, however, Gen-Probe has [...]

New Phase III trial of abiraterone in CRPC starts TODAY!

According to a media release from Cougar Biotechnology, a second Phase III clinical trial of abiraterone acetate started today — for men with castration-resistant prostate cancer (CRPC) who have not received chemotherapy.

AUA report and update no. 9: Wednesday, April 29, 2009

Two papers presented at the meeting on Monday this week addressed radical prostatectomy in high risk patients and different applications of androgen deprivation therapy for their impact on overall patient survival, using the Johns Hopkins patient database as their starting point.

New AUA “best practice statement” on use of PSA

The American Urological Association’s complete new statement on the use of PSA is now available on the AUA web site. New consumer- and patient-directed information about PSA testing is now available on the web site of the AUA Foundation.

AUA report and update no. 8: Wednesday, April 29, 2009

Two studies presented at the AUA on Monday dealt with the mortality rates of men diagnosed with prostate cancer and treated with differing types of first line therapy.

The IMPACT trial results: Tuesday April 27, 2009

OK … so here are the results we have all been waiting for for the past few weeks — the data from the IMPACT trial comparing the survival of patients treated with three doses of sipuleucel-T (Provenge) to placebo in men with androgen-independent prostate cancer.

AUA report and update no. 7: April 28, 2009

In an insightful plenary presentation this morning, Dr. Larry Norton offered an explanation of cancer evolution in the individual patient based on the principles of Darwinian evolution and “natural selection .”

AUA report and update no. 6: Monday, April 27, 2009

We learned a few other interesting tidbits during a variety of sessions and conversations today.

AUA report and update no. 5: Monday, April 27, 2009

So Dr Gerry Andriole just completed his presentation of the main results of the REDUCE trial, designed to test the ability of dutasteride (Avodart) to prevent prostate cancer in men believed to be at high risk for this disease — and the results are positive.

AUA report and update no. 4: Monday, April 27, 2009

The American Urological Association (AUA) has issued new guidance on the use of PSA testing in the early detection of prostate cancer.

AUA report and update no. 3: Sunday, April 26, 2009

The following four reports address some other interesting papers and posters presented at the AUA today.

AUA report and update no. 2: Sunday, April 26, 2009

Two important papers presented this afternoon addressed data on the use of toremifene and denosumab on the bones of men receiving treatment with androgen deprivation therapy (ADT).

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