Prostate only vs. whole pelvis radiotherapy for locally advanced and aggressive disease

If a patient is diagnosed with either high-risk prostate cancer that appears to be confined to the prostate or potentially locally advanced disease that may have progressed into nearby pelvic tissues, the question arises whether it is better to simply radiate the prostate alone with curative intent or to radiate both the prostate and the [...]

Prostate cancer radiotherapy in men on warfarin or Plavix

A recent study has assessed the risk of bleeding as a consequence of radiation therapy for localized prostate cancer in men being treated with anticoagulants .

Risk for metastasis post-surgery: a prognostic algorithm

A media release issued last Wednesday from the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, and based on data presented at the recent annual meeting of the American Society for Clinical Oncology (ASCO), is suggesting that it is possible to predict, with greater accuracy, the long-term risk of metastatic disease in men treated surgically [...]

Palliative prostate-specific radiotherapy in men with advanced prostate cancer

It is still not unusual, in large parts of the world, for patients to be diagnosed with prostate cancer and treated with hormone therapy as a first-line treatment or following a period of active surveillance or monitoring — for all sorts of reasons.

Prostatectomy in patients with PSA > 20 ng/ml

Some years have passed since D’Amico and colleagues developed their risk classification system for newly diagnosed prostate cancer patients which placed any patient with a PSA > 20 ng/ml into the high-risk category. And since the introduction of that classification system, we are aware of limited data on the long-term outcomes of surgical treatment of [...]

Brawley et al. on prostate cancer screening

As mentioned on Tuesday this week, an article and an editorial on prostate cancer screening were just published in CA: A Cancer Journal for Clinicians. Initial media reports on the article and editorial implied that the authors were suggesting that there is no value to testing for prostate cancer. Let us be very clear. This [...]

Prostate cancer news reports: Thursday, July 2, 2009

Today’s news reports discuss such issues as: Sextant biopsy in diagnosis of unilateral prostate cancer Aggressiveness of prostate cancer in man diagnosed with PSA < 4 ng/ml The potential of 3T MRI in prostate cancer prognosis pre-surgery Surgical margins and risk for biochemical recurrence post-surgery

Early data from a significant UK series of HIFU patients

This initial report contains inaccuracies and is based solely on the abstract of the original paper. A more detailed and accurate assessment of this paper was developed on July 4 after assessment of the complete published paper. Readers are advised to read newer report but you can

ADT and changes in cognitive performance

A new — but very small and short-term study — has attempted to assess the baseline prevalence of cognitive impairment in older men treated with androgen deprivation therapy (ADT) and changes in cognitive performance over time.

Prostate cancer news reports: Wednesday, July 1, 2009

In today’s news reports we cover items on: Prediction of risk for prostate cancer under-grading based on biopsy data The obesity/risk equation in prostate cancer Capecitabine + docetaxel in metastatic CRPC

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