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	<title>Comments on: Does ADT3 really work? The TARP study</title>
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	<link>http://prostatecancerinfolink.net/2009/10/29/does-adt3-really-work-the-tarp-study/</link>
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	<item>
		<title>By: Sitemaster</title>
		<link>http://prostatecancerinfolink.net/2009/10/29/does-adt3-really-work-the-tarp-study/#comment-10115</link>
		<dc:creator><![CDATA[Sitemaster]]></dc:creator>
		<pubDate>Sat, 16 Oct 2010 15:38:43 +0000</pubDate>
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		<description><![CDATA[True ... but then that&#039;s why the TARP study is being carried out.]]></description>
		<content:encoded><![CDATA[<p>True &#8230; but then that&#8217;s why the TARP study is being carried out.</p>
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		<title>By: piet</title>
		<link>http://prostatecancerinfolink.net/2009/10/29/does-adt3-really-work-the-tarp-study/#comment-10114</link>
		<dc:creator><![CDATA[piet]]></dc:creator>
		<pubDate>Sat, 16 Oct 2010 14:26:10 +0000</pubDate>
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		<description><![CDATA[&lt;em&gt;n&lt;/em&gt; = 1]]></description>
		<content:encoded><![CDATA[<p><em>n</em> = 1</p>
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		<title>By: Charles (Chuck) Maack</title>
		<link>http://prostatecancerinfolink.net/2009/10/29/does-adt3-really-work-the-tarp-study/#comment-6278</link>
		<dc:creator><![CDATA[Charles (Chuck) Maack]]></dc:creator>
		<pubDate>Fri, 30 Oct 2009 01:22:03 +0000</pubDate>
		<guid isPermaLink="false">http://prostatecancerinfolink.net/?p=7105#comment-6278</guid>
		<description><![CDATA[Forgot to check-mark the &quot;Notify me of follow-up comments via email&quot; so have done so now.]]></description>
		<content:encoded><![CDATA[<p>Forgot to check-mark the &#8220;Notify me of follow-up comments via email&#8221; so have done so now.</p>
]]></content:encoded>
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		<title>By: Charles (Chuck) Maack</title>
		<link>http://prostatecancerinfolink.net/2009/10/29/does-adt3-really-work-the-tarp-study/#comment-6277</link>
		<dc:creator><![CDATA[Charles (Chuck) Maack]]></dc:creator>
		<pubDate>Fri, 30 Oct 2009 01:19:06 +0000</pubDate>
		<guid isPermaLink="false">http://prostatecancerinfolink.net/?p=7105#comment-6277</guid>
		<description><![CDATA[Using myself as one example, on recurrence of my disease in 1996 my urologist put me on an ADT2 protocol with Lupron and bicalutamide/Casodex.  Since it appeared he was leaving me on this protocol indefinitely, my research began.  After 5 years on constant ADT2 I moved to a medical oncologist and stopped both drugs.  1.5 years later my PSA began a rapid rise and by 2 years I returned to ADT but this time added dutasteride/Avodart for triple hormonal blockade/ADT3.  Nearly instant PSA and T drop to castrate levels, so 1 year later again off the Lupron and bicalutamide/Casodex, BUT this time continued the dutasteride/Avodart to continue inhibiting returning T from converting to DHT.  This time it took over 2 years before any rise from &lt;0.01 ng/ml, and in the following 4.5 years my PSA has been on a very slow rise from  &lt;0.01 ng/ml to its most recent 1.16 ng/ml.  My plan is return to bicalutamide (and possibly Lupron) to accompany my continuing dutasteride/Avodart when my PSA reaches 2.0 ng/ml, but at its current rate of increase, that could be another couple of years.  So, for this ADT patient, triple hormonal blockade/ADT3 has worked much more efficiently with the added 5AR inhibitor dutasteride/Avodart than the earlier ADT2 with only Lupron and Casodex.]]></description>
		<content:encoded><![CDATA[<p>Using myself as one example, on recurrence of my disease in 1996 my urologist put me on an ADT2 protocol with Lupron and bicalutamide/Casodex.  Since it appeared he was leaving me on this protocol indefinitely, my research began.  After 5 years on constant ADT2 I moved to a medical oncologist and stopped both drugs.  1.5 years later my PSA began a rapid rise and by 2 years I returned to ADT but this time added dutasteride/Avodart for triple hormonal blockade/ADT3.  Nearly instant PSA and T drop to castrate levels, so 1 year later again off the Lupron and bicalutamide/Casodex, BUT this time continued the dutasteride/Avodart to continue inhibiting returning T from converting to DHT.  This time it took over 2 years before any rise from &lt;0.01 ng/ml, and in the following 4.5 years my PSA has been on a very slow rise from  &lt;0.01 ng/ml to its most recent 1.16 ng/ml.  My plan is return to bicalutamide (and possibly Lupron) to accompany my continuing dutasteride/Avodart when my PSA reaches 2.0 ng/ml, but at its current rate of increase, that could be another couple of years.  So, for this ADT patient, triple hormonal blockade/ADT3 has worked much more efficiently with the added 5AR inhibitor dutasteride/Avodart than the earlier ADT2 with only Lupron and Casodex.</p>
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