http://prostatecancerinfolink.net/2010/02/04/nitroglycerin-for-the-treatment-of-progressive-prostate-cancer/ Tue, 14 Feb 2012 02:28:48 +0000 hourly 1 http://wordpress.com/ http://prostatecancerinfolink.net/2010/02/04/nitroglycerin-for-the-treatment-of-progressive-prostate-cancer/#comment-7307 Mon, 01 Mar 2010 19:52:06 +0000 http://prostatecancerinfolink.net/?p=8130#comment-7307 It seems likely that the ethical issues can be resolved easily because the PSA velocity of prostate cancer is easily measured at either 3- or 6-monthly intervals. Thus for a trial, those who wish could enroll, and there is no need for a double-blind trial or for use of a placebo. The stabilization of PSA velocity is what matters, and the previous track record of PSA velocity is presumably known. This is the course I have personally pursued for 17 years. Selenium and Vitamin E had a minimal impact. No impact with pomegranate juice. A fatty acid synthase inhibitor (Orlistat) caused a NEGATIVE DECLINE in PSA velocity of 40% during the following 12 months. It would be most interesting to combine Orlistat with a nitro patch AND POSSIBLY Estrogel. I should add that my PSA at [diagnosis] was 9.6 ng/ml, with a Gleason of 7. Obviously there may be limitations of any treatment for patients with a Gleason score of 7 or greater.

]]> http://prostatecancerinfolink.net/2010/02/04/nitroglycerin-for-the-treatment-of-progressive-prostate-cancer/#comment-7191 Fri, 19 Feb 2010 00:39:21 +0000 http://prostatecancerinfolink.net/?p=8130#comment-7191 What about those who refuse standard treatment on the grounds of fear of side-effects? Should they not be included in the trials also? If not, why not?

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