Variation in prostate cancer mortality rates in England

According to a report in the Daily Telegraph this morning, there is significant variation is prostate cancer mortality rates across England.

US federal judge invalidates gene patents

In a case that has major ramifications for the health care industry and for personalized medicine, a federal judge in New York yesterday invalidated the patents on BRAC1 and BRAC2 genes held by Myriad Genetics and the University of Utah.

Prostate cancer news reports: Tuesday, March 30, 2010

Today’s news reports address: Diabetes and prostate cancer risk among Japanese men The accuracy of T2w ecMRI in detection of prostate cancer Escalated dose radiation therapy and treatment of localized prostate cancer Erectile dysfunction and penile rehabilitation post-surgery

GSK resubmits data for approval of dutasteride to prevent prostate cancer

According to a media release earlier today, GlaxoSmithKline (GSK) has resubmitted data to the U.S. Food and Drug Administration (FDA) in support of the approval to market dutasteride (Avodart) as a drug to reduce the risk for prostate cancer among men believed to be at high risk.

Should prostate cancer patients start doing Kegels before surgery?

The “New” Prostate Cancer InfoLink has always believed that preoperative training of the pelvic floor muscles (using Kegel exercises) would be likely to improve recovery of continence after radical prostatectomy,

Prostate cancer news reports: Monday, March 29, 2010

News reports over the weekend included: Various review articles dealing with such matters as Gleason grading, numbers of cores taken at biopsy, the need for lymph node dissection, surgical technique and surgical margin control, and cryotherapy The effect of a water extract of white cocoa tea on prostate cancer cells in vitro and in a [...]

U.S. health care reform and prostate cancer — today and tomorrow

Neither The “New” Prostate Cancer InfoLink nor the vast majority of Americans really look at the recent health care reform controversy as “all good” or “all bad.”

Post-treatment mortality of elderly men with high-risk prostate cancer

New data from a series of > 700 elderly patients with high-risk prostate cancer suggests that aggressive combination therapy for such men is associated with a reduced risk for prostate cancer-specific mortality.

Metastasis and mortality after treatment for localized prostate cancer

A restrospective review of data from Memorial Sloan-Kettering Cancer Center has provided us with some interesting new data on the progression of prostate cancer over time.

The demise of Combidex / Sinerem

For several years a company initially called Advanced Magnetics (and later known as AMAG Pharma), with its partners, spent a good deal of money developing and seeking approval of a product called ferumoxtran-10.

Dynamic adaptive radiation therapy: an introduction

The two terms “adaptive radiation therapy” and “dynamic adaptive radiation therapy” are likely to become much more commonly used in the next few years as the use of these techniques expand out from academic and highly specialized radiotherapy centers into the community setting.

“May” is a word custom-made to mislead us

Every year thousands of published research papers and articles carefully use the word “may” or “could” in a headline or a conclusion … and can lead to misconceptions and misunderstandings as a consequence. There are two perfect examples from today’s news.

Hormone therapy effective in man with PSA > 21,000, but …

An article in just published in Onkologie reports the diagnosis and (short-term) treatment of widely disseminated, metastatic prostate cancer in a 64-year-old Croatian man with a PSA of > 21,000 ng/ml.

How preconceptions impact prostate cancer management

As Leah wrote in a comment on this blog just the other day, “Yes, the ‘D-word’ is still taboo. Death is UNAMERICAN.” The comment stimulated the thought that our preconceptions have significant impact on how we think about risk, diagnosis, and treatment of prostate cancer — and yet there is really very little good research on [...]

Active surveillance for prostate cancer: an NCCN update

In a long media release today, the National Comprehensive Cancer Network (NCCN) encapsulated a presentation at the NCCN’s 15th Annual Conference by Dr. James L. Mohler, in which he discussed the role of active surveillance and other treatment options recommended in the recently updated NCCN Guidelines™ for Prostate Cancer.

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