Cost of Provenge set at $93,000 for a course of treatment

There has been a lot of speculation as to what Dendreon would charge for a course of treatment with sipuleucel-T (Provenge). For 2 years, The “New” Prostate Cancer InfoLink has been telling readers that we expected this price to be not less than $75,000.

A prognostic test for low risk of progression post-surgery

IRIS Molecular Diagnostics has submitted an application to the U.S. Food and Drug Administration to market a prostate cancer prognostic test called NADiA® ProsVue™.  The company says that this test is “designed to help physicians identify patients at low risk of cancer recurrence post radical prostatectomy.”

What can happen “In a New York Minute” …

On April 13, 2010, Dan Zenka learned he had prostate cancer. … But why would we call this out as being of any special note

FDA approves Provenge

The US Food and Drug Administration has just announced that sipuleucel-T (Provenge) is approved for the treatment of patients with “asymptomatic or minimally symptomatic prostate cancer that has spread to other parts of the body and is resistant to standard hormone treatment.” Click here to see a copy of the FDA’s media release.

High-dose ketoconazole + docetaxel for treatment of CRPC?

Docetaxel + prednisone is the current standard treatment for men with castration-resistant prostate cancer (CRPC). However, the survival benefit of this form of treatment is small compared to older forms of therapy.

Media highly focused on expected Provenge approval

There has been a flurry of media stories as the “drop dead date” for a decision about approval of sipuleucel-T (Provenge) gets closer and closer.

C-reactive protein as a marker for prostate cancer survival

Evidence continues to accumulate that serum levels of C-reactive protein (CRP) may have value as a prognostic marker for survival in men with very early and very late-stage forms of prostate cancer.

A big “next step” in targeting radiation therapy within the prostate?

In February this year we noticed the abstract of a paper about “The use of dynamic contrast-enhanced (DCE) imaging for delineation of prostate tumors” and the use of “probability mapping” to assist in the treatment planning process.

Relapse-free survival of non-metastatic patients treated with primary androgen deprivation

Many patients with no specific evidence of metastatic disease now receive primary androgen deprivation therapy (PADT) much earlier than was the case before the availability of the PSA test. This includes patients who get hormone therapy for a rising PSA after other forms of first-line therapy and patients who receive hormone therapy as their first-line [...]

Vitamin D and prostate cancer — the saga continues

There is significant evidence that serum levels of vitamin D have impact on the overall health of people as they age, and there has been some (largely laboratory-based) evidence of a specific association between vitamin D levels and risk for prostate cancer.

Early clinical trial of new monoclonal antibody for treatment of CRPC

TRACON Pharmaceuticals has announced the initiation of a Phase I/II clinical trial of its investigational monoclonal antibody TRC 105 for the treatment of patients with metastatic, castration-resistant prostate cancer (CRPC).

It’s crunch week for Provenge

This is the week that the US FDA is expected to announce approval of the first “cancer vaccine” in the USA — sipuleucel-T (Provenge) for the treatment of hormone-refractory prostate cancer. This is a big deal for all sorts of reasons. There was an interesting article in Saturday’s Seattle Times on cancer vaccines in general [...]

When journalists define the “gold standard” for prostate cancer treatment

Reports occur in the media on a regular basis in which journalists talk about their personal experiences in diagnosis and treatment of prostate cancer. These reports can be misleading because,

If you decide to donate your body for prostate cancer research …

… after you pass away, this is the sort of study that you may be able to watch it be used for (always assuming that there is actually a life after death and that you have the ability to observe what happens to your prior “vessel”).

The need to treat “the whole man” — not just his cancer

Results from an international survey of patient perceptions about their prostate cancer treatment were announced yesterday.

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