More unconvincing data about diet and cancer risk

Analysis of data from an 8-year-long European trial has concluded that a diet high in fruits and vegetables has only modest impact on people’s risk for cancer — but the study was again so flawed that it is hard to know what it really shows.

The CaP Calculator: a new, sophisticated, decision-support tool

Long, long ago (in September 2008), we initially reported on the existence of a prostate cancer decision support tool (then in very early-stage development) known as the CaP Calculator.

Predicting progression of low-risk patients on active surveillance

A recent article from a team at Johns Hopkins provides information about the ability to predict biopsy-based progression among their surveillance cohort of men with low-risk prostate cancer.

Should PSA levels be “undetectable” at 5 years after successful brachytherapy?

Most brachytherapy centers today use the Phoenix criteria to define clinical success and failure after brachytherapy. But a new paper suggests that brachytherapy can (and perhaps should) use a higher standard for long-term follow-up.

High-dose bicalutamide as second-line hormone therapy in CRPC patients

Historically there have been few really compelling data available to support the use of an additional or alternative antiandrogen as a second-line agent to extend either progression-free or overall survival of castration-resistant prostate cancer (CRPC) patients who progress after first-line hormone therapy (whether they have been treated by orchiectomy or medical castration with an LHRH [...]

Quality of life after first-line treatment: a prospective, comparative study

Data to be published in the May 2010 issue of the Journal of Urology are going to make a lot of urologists rather less than happy about the implications for the use of radical prostatectomy as first-line treatment for prostate cancer.

Robert Benjamin Ablin, R.I.P.

Most days the wise man will try to learn something he didn’t know when he got up that morning. Sometimes that can be hard work. This morning your correspondent got lucky.

Data from a 300+ patient series treated with CyberKnife

Stereotactic body radiotherapy (SBRT) — aka CyberKnife radiotherapy — is among the most recent methods developed for the treatment of prostate cancer using radiation. People have been waiting a while now to see early data from a large series of patients.

Prostate cancer news reports: Saturday, April 3, 2010

Today’s news reports deal with such items as: The effects of antiretroviral drugs for HIV/AIDS on the XMRV virus Diet, milk, and prostate cancer etiology Can saturation biopsies really identify low-risk cancers? Prostate weight and prostate cancer recurrence

PSA testing in men aged 75 years and older

The “New” Prostate Cancer InfoLink has long taken the position defined by the Iowa Consensus, that PSA testing in men aged 75 and older should be based on the health characteristics and life expectancy of individual patients, as compared to an arbitrary cut-off of PSA testing in all men at age 75 years.

Anxiety and distress during active surveillance

A Dutch research group has published follow-up data related to their continuing evaluation of anxiety and distress levels among men with low-risk, loocalized prostate cancer who are managed with active surveillance at their institution.

Vitamins C and E don’t protect against prostate cancer; what about vitamin K?

Data from a prospective study now suggest an association between dietary levels of vitamin K and one’s risk of developing or dying from colon, breast, prostate, or lung cancers.

Data from the REDUCE trial published in NEJM

The final report from the REDUCE trial was published this morning in the New England Journal of Medicine. Most of these data were initially presented last year at the annual meeting of the American Urological Association (as reported at the time). However, there are two small problems.

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