Does topography of cancer in the prostate correlate to risk for positive lymph nodes?

An interesting new report from the research team at Memorial Sloan-Kettering Cancer Center has explored the relationship between the patterns of occurrence of positive lymph nodes (LNs) and the topography of the cancer in the prostate and the seminal vesicles.

The continuing importance of primary Gleason pattern 4 in Gleason 7 prostate cancer

It has long been understood that men with a Gleason score (GS) of 7 could be divided into two groups: those with Gleason 4 + 3 disease (in which Gleason pattern 4 was more common or “dominant”) and those with Gleason 3 + 4 disease (in which Gleason pattern 3 was dominant).

Regular exercise and prostate cancer-specific survival

According to a new analysis of data from participants in the Health Professionals Follow-Up Study, regular physical activity is associated with an overall and a prostate cancer-specific survival benefit in men initially diagnosed with prostate cancer who show no signs of metastasis at diagnosis.

ACR and ASTRO issue new guideline on brachytherapy

The American College of Radiology (ACR) and the American Society for Radiation Oncology (ASTRO) have jointly issued a new guidance document on the treatment of prostate cancer with permanent radioactive “seed” implants inserted through the perineum.

Consumer Reports on first-line management of prostate cancer

There is an interesting summary of the major, first-line management options for localized prostate cancer in today’s Washington Post. It has been prepared by the Consumer’s Union (publisher of Consumer Reports) as part of their Consumer Reports Insights series.

Why do some nutritional supplements seem to delay prostate cancer progression?

It is widely recognized that some nutritional supplements and other dietary products seem to to have some effect on risk of prostate cancer progression. The problem is that we really don’t know why or how.

Will the FDA be approving ipilimumab relatively soon?

Apparently the U.S. Food & Drug Administration (FDA) has canceled a  meeting of the Oncology Drugs Advisory Committee (ODAC) that had been scheduled for February 9. The meeting was originally intended to discuss issues related to a biologics license application for ipilimumab (trade name Yervoy™).

New, chip-based technology can isolate, identify prostate cancer cells in blood

According to an Associated Press story that came out this morning, Johnson & Johnson and “Boston scientists” are working together on “A blood test so sensitive that it can spot a single cancer cell lurking among a billion healthy ones.”

NCCN issues patient guidelines on prostate cancer diagnosis and management

At some point in the past 3 weeks or so, the National Comprehensive Cancer Network (NCCN) Foundation has quietly issued its new NCCN Guidelines for Patients™ on prostate cancer diagnosis and management.

Active surveillance gets a major endorsement — in Oz

Awareness of brachytherapy as a treatment for localized prostate cancer was revolutionized in the U.S. in 1996 — not by a doctor but by a patient.

Major expectations from the clinical research front in 2011

There are three major prostate cancer research studies that we expect or hope to hear results from at some time in 2011.

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