“Five prostate cancer diagnostics to watch”

The FierceBiomarkers e-newsletter has compiled a brief report with the above title that may be of interest to some of our readers.

It’s time to badger Congress — yet again, pretty please!

Many readers will already have seen the report we posted about Senator McCain’s desire to eliminate the Prostate Cancer Research Program within the Congressionally Directed Medical Research Program (CDMRP) — one of the most successful prostate cancer research initiatives. Now you can work with the rest of the advocacy community to counter this.

Outcomes after HIFU and prognosis based on post-HIFU PSA nadir levels

A new analysis of data from the multi-center @-Registry of patients undergoing Ablatherm-based high-intensity focused ultrasound (HIFU) for the treatment of localized prostate cancer suggests that nadir levels of PSA post-treatment can be used to predict the probability of biochemical progression-free survival (bPFS) at 5 years of follow-up.

Are we (still) over-treating older men with localized prostate cancer?

There is good reason to believe that a very high percentage of older men — particularly those over 75 years with low-risk prostate cancer who have a life expectancy of 10 years or less — will get little to no clinical or survival benefit from active therapeutic intervention (although they should clearly be carefully monitored [...]

Another update on statins in prostate cancer

Out of the 600+ presentations at the IMPaCT meeting in Orlando last week, your correspondent somehow managed to overlook an interesting poster that offers new evidence in support of the potential benefit of statin therapy in the prevention and management of prostate cancer.

Prevalence of prostate cancer in the U.S.A.

A report from the Centers for Disease Control, issued last week, suggests that as of January 1, 2007 there were nearly 2.3 million men living in the U.S. after a diagnosis of prostate cancer.

One urologist’s opinion … on the value of “high tech” medicine

Craig Turner, MD, practices urology in Portland, Oregon, and for the past 6 years or so he has been carrying out laparoscopic radical prostatectomies with the help of a da Vinci robot … but he doesn’t seem to think this has made him a better prostate cancer surgeon.

Follow-up after finding of “atypia” on initial prostate biopsy

It has long been understood that a finding of “atypia” (atypical small acinar proliferation) on an initial biopsy of the prostate is associated with an increased risk for prostate cancer, and a repeat biopsy is normally recommended for any patient with an initial finding of atypia.

Tertiary Gleason grades and consequent prognostic risk

We have known for a while that men with a tertiary Gleason grade of 4 or 5 (as  discussed below) are at heightened risk for progressive forms of prostate cancer.

Building familial risk into prostate cancer testing decisions

The PCPT prostate cancer risk calculator is a widely used tool designed to help men and their doctors assess whether they should have a prostate biopsy based on the patient’s age, PSA level, and supplementary data. The calculator asks about family history of prostate cancer in one simple question requiring only a Yes/No answer.

Adamis files IND to initiate clinical trials of APC-100 in mCRPC

According to a media release on the BusinessWire web site earlier this week, Adamis Pharmaceuticals has filed an Investigational New Drug (IND) application with the U.S. Food & Drug Administration seeking the ability to initiate a 30-patient Phase I/IIa clinical trial

48 hours at the IMPaCT symposium in Orlando: Part III

So the question any smart prostate cancer patient should ask himself — especially if he has any degree of good scientific education — is, “How do I get myself invited to the next IMPaCT meeting?”

48 hours at the IMPaCT symposium in Orlando: Part II

One of the other major initiatives that have been funded over several years by the Department of Defense’s Prostate Cancer Research Program is the North Carolina-Louisiana Prostate Cancer Project (often just known as PCaP).

48 hours at the IMPaCT symposium in Orlando: Part I

Most medical-scientific meetings that deal (at least in part) with prostate cancer are inhabited by academic scientists, clinicians, and various types of representative of commercial companies.

Senator McCain wants to cut funding for prostate cancer research by $80 million

Senator John McCain is a man who has been treated successfully not once, not twice, but three times for malignant melanoma.

Follow

Get every new post delivered to your Inbox.

Join 249 other followers