“Unrealistic optimism” and participation in early-stage clinical trials

There is an excellent article by Pauline Chen in today’s New York Times. It is focused on the mindsets of patients who willingly participate in the very earliest clinical trials of  new drugs for the treatment of cancer, and on ethical issues related to enrollment of patients into these trials.

Co-morbidity, age, mortality, and early-stage prostate cancer

New data from Peter Albertsen and his colleagues at the University of Connecticut have emphasized the importance of thorough assessment of the health status and co-morbidities of older men who are diagnosed with prostate cancer before making decisions about appropriate management.

Understanding the risk-based approach to prostate biopsy

There is an interesting interview with Dr. Chris Parker of the Marsden Hospital in the UK on the OncologySTAT web site this week. To be able to read this interview in full, you do have to be a registered member of the OncologySTAT web site, but there is no charge for this membership

Vitamins, supplements, and prostate cancer-related risk

Many men use vitamins and other supplements to prevent the onset of prostate cancer or to prevent the progression of prostate cancer after diagnosis. However, a new article in Family Practice suggests that there is no really good clinical evidence for either of these practices in the published literature.

Another possible urine test for detection of prostate cancer?

A study just published in Clinical Cancer Research suggests that levels of a protein called engrailed-2 (EN2) in urine may be indicative of risk for prostate cancer.

Vitamin D, cancer prevention, research data, and media releases

There is an interesting article just published in Anticancer Research that comes to the conclusion that, “Universal intake of up to 40,000 IU vitamin D per day is unlikely to result in vitamin D toxicity.” However, one needs to interpret the content of this article — and this conclusion — with some care.

Was prostate cancer really the cause of death?

One of the most complicated questions in dealing with prostate cancer is correctly assessing whether men who are known to have had prostate cancer actually died of their prostate cancer or simply with it, especially among men of more advanced age or with co-morbid conditions. In other words, “What do prostate cancer patients die of?”

Follow

Get every new post delivered to your Inbox.

Join 249 other followers