Mortality and management of locally advanced prostate cancer with non-curative intent

A fascinating new paper based on data from the Prostate Cancer DataBase Sweden provides important insight into the consequences of delayed diagnosis and potential under-treatment of men who are diagnosed with locally advanced prostate cancer.

Outcomes after surgery for spinal cord compression among men with metastatic prostate cancer

Spinal cord compression is a relatively common consequence of advanced, metastatic prostate cancer. Treatment has historically involved reconstructive surgery to relieve the compression and stabilize the spine.

Targeting the 5α-reductase enzyme in treatment of prostate cancer

A recent review article concludes with the statement, “5α-reductase inhibition does seem to have beneficial effects on prostate cancer incidence, and the role of [5α-reductase inhibitors (5-ARIs)] in combination with other agents should be further evaluated for the treatment of [castration-resistant prostate cancer (CRPC)].”

Eating whole-grain products doesn’t reduce risk for prostate cancer

Perhaps to be more strictly accurate we should rephrase that heading as, “A diet high in whole-grain products did not appear to reduce the risk for prostate cancer among a large cohort of Danish men aged between 50 and 64 years.”

CAPRA-S scores and projection of prostate cancer recurrence post-surgery

The University of California, San Francisco (UCSF) Cancer of the Prostate Risk Assessment (CAPRA) score was initially introduced in 2005 and validated in 2006 as a pre-treatment tool that could be used to assess risk for prostate cancer recurrence after first-line treatment.

Can ultrasensitive PSA at 3 years post-surgery project delayed BCR?

A research team at New York University School of Medicine has reported data suggesting that a single ultrasensitive PSA test result may be able to project risk for delayed biochemical recurrence (BCR) of prostate cancer at 3 years after a radical prostatectomy.

Andy Pollack on new prostate cancer treatments in the New York Times

Many prostate cancer patients and advocates will want to read yesterday’s article by New York Times correspondent Andrew Pollack entitled, “New drugs fight prostate cancer, but at high cost.” The article offers a commentary on recent advances in the treatment of advanced prostate cancer — and the economic consequences.

Amgen requests expanded indication for denosumab

As expected (and as previously discussed on this site), Amgen has submitted a supplemental Biologics Licensing Application (sBLA) for denosumab (Xgeva®) for the prevention or the delay of the spread of prostate cancer to bone in men with castrate-resistant prostate cancer (CRPC).

CTCs from patients with CRPC have specialized markers

A team of researchers at Duke University have shown that most men with castration-resistant prostate cancer (mCRPC) express multiple epithelial proteins in their circulating T cells (CTCs).

The role of exercise in prostate cancer management

Prostate cancer patients in general, but most especially men receiving androgen deprivation therapy (ADT), experience symptoms  and side effects of treatment that make it difficult to maintain their independence and quality of life. A recent review states that exercise may offset many of the side effects of ADT as well as those of the cancer [...]

Surprise! Being married improves prostate cancer survival

It has been known for years that marital status impacts the likelihood of stage at diagnosis and survival in a number of different types of cancer (prostate cancer included). However, a new study has now confirmed this in a large, US, population-based analysis of prostate cancer patients.

NIH to run state-of-the-science conference on active surveillance

On December 5 to 7 this year, the National Institutes of Health (NIH) is to hold an NIH State-of-the-Science Conference on the role of active surveillance and watchful waiting in the management of men with supposedly localized prostate cancer. It is free and open to the public or it can be monitored by web cast.

Please help us to publicize this site

A web site called GreatNonProfits is running a health competition through the end of June. We would like your help to use this competition to promote awareness of the services of Prostate Cancer International — particularly The “New” Prostate Cancer InfoLink and and the associated social network. So

R.I.P. … the demise of Google Health

Any readers of this web site who have been using Google Health as a technology to store personal health data should click on this link.

Prostate cancer-specific mortality rate dropping in France

An article in Progrès en urologie states that the prostate cancer-specific mortality rate in France has been dropping by 2.5 percent per year.

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