Potential future agents in the management of mCRPC

A new article by Antonarakis and Armstrong in full text on the Medscape web site reviews available information on a wide range of currently investigational agents for the treatment of metastatic, castration-resistant prostate cancer (mCRPC), including

Roundtable issues media release re USPSTF recommendation

In addition to the formal letter submitted to the U.S. Preventive Services Task Force (USPSTF), and noted on this web site on Friday, the Prostate Cancer Roundtable has, this morning, also issued a media release, signed by the same 10 members of the Roundtable.

The USPSTF recommendation: a cartoonist’s perspective

Larry Axmaker is an 8-year prostate cancer survivor and very happy he had regular PSA screenings!

Survey suggests high level of long-term side effects after treatment for prostate cancer

According to new data presented at the Frontiers in Cancer Prevention Research meeting ongoing this week in Boston, MA, some 70 percent of prostate cancer patients participating in a survey in Michigan reported long-term, treatment-related, adverse effects after first-line treatment with surgery or radiation therapy.

Prostate Cancer Roundtable comments on USPSTF recommendation

Ten members of the Prostate Cancer Roundtable have today submitted a joint letter to the U.S. Preventive Services Task Force commenting on the recent draft recommendation of a “D” grade for use of the PSA test in screening for prostate cancer among men who do not have symptoms that are highly suspicious for prostate cancer, [...]

Are changes in PSA kinetics potentially indicative of metastasis-free survival?

Researchers at Johns Hopkins have provided data to support the hypothesis that, in men being treated with novel, non-hormonal agents for non-metastatic, non-castrate, biochemically recurrent prostate cancer after first-line therapy, changes in PSA kinetics may be indicative of metastasis-free survival.

Low fat diet + fish oil lowers risk for prostate cancer cell proliferation

Data from a prospective, randomized, Phase II clinical trial have shown that men diagnosed with early stage prostate cancer can decrease their risk for prostate cancer cell proliferation through use of a low-fat diet and fish oil capsules.

PSA screening today: four points of view in the NEJM

This week’s issue issue of the New England Journal of Medicine includes four perspective articles on the recent draft recommendation about PSA screening issued by the U.S. Preventive Services Task Force (USPSTF).

“Screening saved my life.” Just how accurate is that claim?

A report on the CNBC web site today discusses an article published earlier this week in the Archives of Internal Medicine. The premise of this article is that for the majority of women diagnosed with breast cancer who claim that their life was saved by a mammogram, there is limited justification for this highly emotionally, [...]

What happens next after a baseline PSA test?

According to data from a prospective study of prostate cancer outcomes conducted by researchers at the Mayo Clinic, the PSA test is “valuable in predicting which men should have biopsies and which are likely to be diagnosed with low-risk prostate cancer.”

Major new cancer clinical and genetic database to be built in Boston

According to an article published today in The Boston Globe, the Dana-Farber Cancer Center and Brigham and Women’s Hospital are working together to initiate development of a very large, cancer-specific, genetic and clinical database.

Another investigational test may refine data on need for prostate biopsy

A newly published paper  in the Journal of Urology describes a multi-center, prospective study of the potential of the investigational, urine-based, ProCaM™ assay as a test to offer improved evaluation of the need for prostate biopsy among men with an initial total serum PSA level between 2 and 10 ng/ml.

Quality of life after initial watchful waiting compared to immediate treatment

According to another publication based on data from the Physicians’ Health Study, “Quality of life outcomes in men who underwent delayed treatment after initially waiting were not worse than in men who underwent immediate treatment.”

3 Tesla MRI imaging and the diagnosis of localized prostate cancer

It has been noted previously in this blog that we are improving our ability to accurately identify localized prostate cancer using several types of imaging technology.

Age-related diagnosis with M1 disease and age-related prostate cancer-specific mortality rates

According to a media release from the University of Rochester, a new study suggests that “men age 75 and older are diagnosed with late-stage and more aggressive prostate cancer and thus die from the disease more often than younger men.”

Follow

Get every new post delivered to your Inbox.

Join 249 other followers