Radiation therapy may improve survival even when PSA ≥ 75 ml/ml

Sometimes, when patients originally present with very high PSA levels, a negative bone scan, and a negative CT scan, they are put on permanent androgen deprivation  therapy (ADT) because the doctor just assumes it is micrometastatic. … READ MORE …

Active surveillance under-used (back in 2010-2011)

A new research letter just published in JAMA Internal Medicine suggests that only about 12 percent or less of the men who are good candidates for active surveillance are actually being managed in that manner. But, … READ MORE …

The impact of bicycling on PSA levels … and risk for prostate cancer

Over the years it has been suggested, on and off, that bicycling may have impact on a man’s PSA levels and therefore on his potential risk for diagnosis of prostate cancer. However, there has never been any real evidence of such impact. … READ MORE …

Active surveillance, upgrading on repeat biopsy, and consequent management

In February this year we commented on an article that argued in favor of active surveillance as an appropriate initial management strategy for “favorable” intermediate-risk prostate cancer. … READ MORE …

Tokai initiates trial of galeterone in men with AR-V7-positive mCRPC

According to information released earlier today by Tokai Pharmaceuticals, the company has started to enroll patients with AR-V7-positive, metastatic, castration-resistant prostate cancer (mCRPC) into a randomized Phase III clinical trial of treatment with galeterone. … READ MORE …

Does diagnosis/treatment for prostate cancer increase risk for colorectal cancer too?

A newly published study in the journal of Cancer Control has again suggested the possibility that men treated for prostate cancer may be at elevated risk for a secondary diagnosis of colorectal cancer by comparison with similar men never diagnosed with prostate cancer. … READ MORE …

The NCCN patient guidelines have “come of age”

Over the past weekend, we were able to review the most recent update to the National Comprehensive Cancer Network’s guidelines on treatment of prostate cancer for patients. It is our considered opinion that this booklet is now among the very best basic introductions to prostate cancer management for any newly diagnosed patient and his family. … READ MORE …

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