Is leucine blockade an important new approach to prostate cancer management?

Newly reported research from a team at the Centenary Institute in Sydney, Australia, has suggested a very different way in which it may be possible to significantly delay or manage the progression of prostate cancer.

Selenium in treatment of men with HG-PIN to prevent prostate cancer

The SELECT study has previously shown that treatment with selenium did not prevent prostate cancer in your average “guy in the street.” However, what about men with a prior diagnosis of high-grade prostatic intraepithelial neoplasia (HG-PIN)?

Eggs, prostate cancer, and the Daily Mail

Our friends at The Daily Mail in the UK have been spreading a story that men who eat 2.5 eggs or more a week have an 81 per cent increase in their risk for lethal prostate cancer compared to men who do not.

Saw palmetto extract does not shrink prostate size (redux)

Saw palmetto extract (made from the berries of the saw palmetto plant, Serenoa repens) is widely used by many men to prevent or treat benign enlargement of the prostate (benign prostatic hyperplasia). While it is not known to have any effect on prostate cancer, the use of saw palmetto has long been a topic of [...]

FDA expands approval of denosumab in men with advanced prostate cancer

According to a media release issued by Amgen earlier today, the U.S. Food & Drug Administration (FDA) has approved denosumab (marketed as both Prolia® and Xgeva®) as a treatment to increase bone mass in in men with non-metastatic prostate cancer who are already being treated with androgen deprivation therapy (ADT) and who are at high [...]

But does it make a blind bit of difference?

In a newly published paper in the journal Integrative Cancer Therapies, the authors report high use of vitamins and supplements among undiagnosed men with a brother who has previously been diagnosed with prostate cancer.

Whole ginger extract in prostate cancer prevention and treatment

The full text of a new article on the potential of whole ginger extract (WGE) in the prevention and treatment of of prostate cancer has recently been published in the British Journal of Nutrition.

Complementary and alternative medicine and prostate cancer care

The current issue of Urologic Clinics of North America, edited by Mark Moyad, MD, of the University of Michigan Medical Center, includes a series of review articles dealing with complementary and alternative care in the prevention and management of urologic disorders in general and prostate cancer in particular.

Diet and prostate cancer risk: a case-control study analysis

The idea that one’s diet may affect one’s risk for prostate cancer in general — or perhaps for one’s risk of more aggressive forms of prostate cancer — is not exactly new.

5α-Reductase-III and its potential in prevention/treatment of prostate cancer

There are in fact three so-called “isozymes” (slightly different versions) of the human enzyme 5α-steroid reductase. The activity of 5α-reductase-II can be affected by the 5α-reductase inhibitor (5-ARI) finasteride (Proscar); the activity of 5α-reductase-I and -II can be affected by the 5-ARI dutasteride (Avodart), but

Of genetics, diabetes, and prostate cancer risk

We know from a number of older, epidemiologic studies that there seems to be an inverse association between diabetes status and prostate cancer risk. In other words, people with diabetes seem to be less likely to be diagnosed with prostate cancer.

Vitamin D supplements may increase prostate cancer risk (at least among Finnish smokers)

Proving the point that (at least in prostate cancer) if you look carefully enough you can always find a study that supports your particular point of view, a new report from researchers at the National Institutes of Health and partner organizations has now demonstrated that, “High blood levels of vitamin D may increase a man’s [...]

Lycopene and prostate cancer prevention in African American men

Over the years there has been much noise and little good data regarding the effects of lycopene in the prevention of prostate cancer. Indeed, all we can really say today is that there is an association between eating tomato-based products and a reduced risk for prostate cancer.

AUA comments on FDA guidance on safe use of 5-ARIs

The American Urological Association (AUA) has written to the U.S. Food & Drug Administration (FDA) seeking modification of the FDA’s recent guidance on the use of 5α-reductase inhibitors like dutasteride and finasteride in the management of urologic conditions.

Eating whole-grain products doesn’t reduce risk for prostate cancer

Perhaps to be more strictly accurate we should rephrase that heading as, “A diet high in whole-grain products did not appear to reduce the risk for prostate cancer among a large cohort of Danish men aged between 50 and 64 years.”

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