Please badger your Congressperson TODAY

With reference to the need to keep funding high for the Prostate Cancer Research Program (see yesterday’s story), please make sure that you call or write your Congressman or Congresswoman was early as possible TODAY. You have until about 5 pm Eastern time here in the USA to get messages in to your representative asking [...]

In Europe, just because it’s approved doesn’t mean you can get it …

The complexity of access to new agents for the treatment of prostate cancer in countries around the world is not necessarily evident to all our readers, so, just as an example, here is the situation as of today regarding access to abiraterone acetate in the UK alone:

New abiraterone data to be submitted for presentation at ASCO in June

We are now able to confirm that the full results of the Phase III trial of abiraterone acetate + placebo in the treatment of men with chemotherapy-naïve, metastatic, castration-resistant prostate cancer are being submitted for approval

Survival after a diagnosis of AJCC Stage IV prostate cancer

For many men, a diagnosis of prostate cancer of any stage or grade — even of the lowest level of risk — is hard to deal with. If they have progressive disease after first-line therapy, it may appear to be an overwhelming issue.

Additional data supportive of clinical value of Prolaris test

A new report in the British Journal of Cancer suggests that data provided through Myriad Genetics’ Prolaris™ test may be “the strongest independent predictor of cancer death outcome yet described” for the management of men with clinically localized prostate cancer.

The NCI’s “provocative questions” project: the current 24 questions

A key initiative introduced by Dr. Harold Varmus after he took his current position of Director of the National Cancer Institute (NCI) here in the USA was the “provocative questions” project. His idea was that we should try to identify a small number of really focused questions about cancer and base research funding around seeking [...]

Vigorous exercise may prevent progression of low-risk prostate cancer

The idea that exercise and physicial fitness may be associated with a reduction in risk of disease progression in men with relatively low-risk prostate cancer is hardly new, but

Dutasteride as a single agent for low-risk prostate cancer

According to data just reported in The Lancet, some men with low-volume, low-risk prostate cancer may be able to delay progression of their disease if treated only with the 5α-reductase inhibitor dutasteride (Avodart®).

An update on views about the USPSTF recommendation and prostate cancer screening

Apparently, earlier this week, Congressmen Runyan and Baca (the co-chairmen of the Congressional Prostate Cancer Task Force) sent a letter to Secretary Sebelius about prostate cancer screening.

Self-referral and the role of IMRT in treatment of prostate cancer

The issue of whether some urology practices are investing in equipment capable of delivering intensity-modulated radiation therapy (IMRT) with financial motives is back on the front burner again.

A small, multi-center cohort study of SBRT in treatment of low-risk prostate cancer

Published reports on the safety and efficacy of extreme hypofactionated radiation therapy (stereotactic body radiation therapy or SBRT, a.k.a. CyberKnife radiation therapy) have, to date, come from just a couple of key centers.

Single genetic mutation predicts risk for one rare form of hereditary prostate cancer

According to an article in today’s New England Journal of Medicine, a rare but recurrent mutation in a gene known as HOXB13 (rs138213197) — a gene that is important in prostate development — appears to be responsible for early-onset, familial prostate cancer in some men of European descent.

The scientific basis for PSA monitoring after first-line treatment for localized prostate cancer

A new article in the Canadian Medical Association Journal has reported on a careful analysis of the published literature underlying current guidelines on the use of repetitive PSA testing to monitor risk for progression in men receiving first-line treatment for localized prostate cancer.

Are US urologists really acceptant of active surveillance?

According to a new study published on line in Prostate Cancer and Prostatic Diseases, 370/425 urologists who responded to a recent survey felt that active surveillance was a reasonable management strategy and about 350/425 actually manage patients by using this approach. But

ACS projects incidence and mortality data for 2012

The American Cancer Society (ACS) yesterday released projected data for the incidence and the mortality of prostate cancer for 2012. The bottom line: they are projecting more new cases and significantly fewer deaths than in 2011.

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