UroToday interviews with D’Amico, Klotz, Mulhall

Many readers of this blog may be interested in listening to one or more of a series of recent, relatively short audio-interviews with respected opinion-leaders in the prostate cancer diagnosis and management community, conducted by the medical director of UroToday. … READ MORE …

Use of expectant management more than doubles since 2004

According to a presentation at the Genitourinary Cancers Symposium, there has been a significant, recent increase in the numbers of men with low-risk prostate cancer who get care in the USA through some form of expectant management (active surveillance, watchful waiting, etc.). … READ MORE …

One man’s route to active surveillance as a first-line management strategy

When CT learned that he had low-grade, organ-confined prostate cancer, he did not decide to get surgical or other therapeutic interventions immediately, based on the guidance of the first doctors he saw. Instead, he decided to actively monitor his disease and adjust his lifestyle habits with guidance from a team of specialists. … READ MORE …

How low is the risk for Gleason score progression over time?

A new study report in Cancer Research suggests that: (a) prostate cancer aggressiveness may be established when the initial tumor is formed and not alter over time; (b) active surveillance or similar monitoring strategies really are the most appropriate initial management option for men with low-grade, low-risk cancer (potentially regardless of their age at diagnosis). … READ MORE …

Active surveillance and racial difference in risk

A new article in Urology (“the Gold journal”) suggests that African American men diagnosed with low-risk forms of prostate cancer may need to meet more stringent criteria than Caucasian Americans if they are to be appropriately managed on active surveillance protocols. Why? Because they appear to be at higher risk for disease progression. … READ MORE …

Counseling and support associated with active surveillance: highly necessary for some

It is well understood that some (perhaps even many) men diagnosed with low-risk disease have difficulty accepting active monitoring of any type as an effective and safe management strategy for deferring immediate, unnecessary treatment  — and perhaps being able to avoid treatment at all. … READ MORE …

National Proactive Surveillance Network goes live in Baltimore and Los Angeles

As reported previously, in May 2010, the Prostate Cancer Foundation, in association with Johns Hopkins and the Cedars-Sinai Medical Center announced their intention to develop a national initiative to track the management of men with prostate cancer using active monitoring  (“active surveillance”) as opposed to invasive treatment. … READ MORE …

Speciality bias still affecting treatment recommendations for low-risk prostate cancer?

A majority of urologists and radiation oncologists are still not recommending active monitoring (“active surveillance”) as a first-line method for the management of patients with low-risk prostate cancer. … READ MORE …

Are we (still) over-treating older men with localized prostate cancer?

There is good reason to believe that a very high percentage of older men — particularly those over 75 years with low-risk prostate cancer who have a life expectancy of 10 years or less — will get little to no clinical or survival benefit from active therapeutic intervention (although they should clearly be carefully monitored and given all appropriate care). … READ MORE …

Three important editorials

The October issue of the Journal of Urology carries three editorials that we consider to be very important to the world of prostate cancer — for professionals and patients alike. … READ MORE …

Your news update: Tuesday, September 16

Today’s news is focused on issues around prevention, screening, and active surveillance:

  • The potential cost-effectiveness of widespread use of finasteride to prevent prostate cancer
  • An update on data from the European Randomized Study of Screening for Prostate Cancer (ERSPC)
  • The argument in favor of active surveillance as first-line management for men with low risk prostate cancer … READ MORE …

Prostate cancer news update: Tuesday, August 26

There are several interesting news items today, as follows:

  • Ethnic variation in the performance of PSA and PSA density as markers for risk of prostate cancer
  • Potential underuse of active surveillance in eligible patients
  • Application of active surveillance in a 40-patient case series
  • The potential to eliminate the need for a urethral (Foley) catheter post-surgery
  • Circulating tumor cell levels as a predictor for response to androgen deprivation therapy … READ MORE …
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