Prostate cancer in younger men: an important new review

An article in this month’s issue of Nature Reviews: Urology has looked closely at a question of significant relevance to an important subset of our regular readers — Is prostate cancer in some way “different” in younger men? … READ MORE …

Risk evaluation among men initially diagnosed with T1cN0M0 disease

A recent paper in Frontiers in Oncology offers us new information about the risk profiles of men initially diagnosed with clinical stage T1c disease in the USA in relatively recent years. … READ MORE …

How one thing that happens in childhood may affect risk for prostate cancer

The “New” Prostate Cancer InfoLink has been pointing out (on a fairly regular basis over the past 5 years) that at least some of our risk for prostate cancer (other than the genetic risks) may be affected by what happens to us in childhood. … READ MORE …

Urologists’ and radiation oncologists’ opinions on use of PSA test to screen for prostate cancer

A new study has provided data on the opinions of a random sample of 1,366 radiation oncologists and urologists with regard to the appropriate role of the PSA test in screening for prostate cancer (since the recommendation of a D grade for this test as a screening mechanism by the U.S. Preventive Services Task Force (USPSTF). … READ MORE …

Dr. David Agus on CBS’s “Morning Rounds”

So the role of prostate cancer screening got discussed on the CBS television program “Morning Rounds” on Saturday, by Dr. David Agus (a well-known urologic oncologist) and others. The context was the recent data on the “overuse” of the PSA test in men of 75+ years of age. … READ MORE …

Life expectancy ≤ 10 years and the risks associated with treatment

According to Reuters, a new article, forthcoming on line in the Annals of Internal Medicine, tells us (not too surprisingly) that, “Older men with other illnesses may not live long enough to benefit from aggressive prostate cancer treatments, such as prostate removal or radiation, and they’d have to live with their side effects.” … READ MORE …

Age, communication, and access to appropriate prostate cancer services/options

Newly reported data from the German HAROW study suggests that older men diagnosed with prostate cancer are less informed that younger men about access to things like patient support groups, post-treatment rehabilitation services, and second medical opinions. … READ MORE …

Elderly and black males at greater risk for aggressive disease?

An epidemiological analysis of data from the Surveillance, Epidemiology, and End Results (SEER) database shows that older and black males have higher risk for intermediate- and high-risk prostate cancer, … READ MORE …

Risk for biochemical failure post-surgery among prostate cancer patients > 70 years of age

A new article from the clinical research group at The Cleveland Clinic has suggested that men > 70 years of age are at significantly higher risk for recurrence of their prostate cancer if treated by radical prostatectomy than younger men with comparable diagnostic criteria. … READ MORE …

Why is likelihood of prostate cancer diagnosis declining?

In an article discussed earlier this week on this web site (click here for more), Howard argued that the USPSTF recommendation to abandon PSA screening in men of ≥ 75 years of age was a key factor in the decrease in the incidence of prostate cancer in men in this age group. But is Dr. Howard right? … READ MORE

Incidence of diagnosis of prostate cancer declines from 2007 to 2009 in USA

According to a brief research letter by Howard, just published in Archives of Internal Medicine, the incidence of prostate cancer diagnosis in men of ≥ 75 years declined significantly after the issuance of the 2008 recommendation by the USPSTF that PSA screening for prostate cancer was not appropriate in men of 75 years and older. … READ MORE …

PSA levels in previously tested and untested American males: what do they tell us?

In a poster to be presented at the upcoming annual meeting of the American Society for Clinical Oncology (ASCO) on Sunday, June 3, Allen et al. have compared the PSA levels of previously tested American men to the PSA levels of American men whose PSA level had never previously been assayed. … READ MORE …

Outcomes after surgery for low-risk disease in men 65 years and older at a major prostate cancer center

Data from the extensive series of patients with clinically localized prostate cancer treated by radical prostatectomy at Johns Hopkins over the past 30 years has shown that men > 65 years of age with low-risk disease had excellent survival after surgery, … READ MORE …

Orgasmic function is not the same as sexual function: what are we really being told?

We are having a hard time with a media release issued yesterday by BJU International in relation to a study just published in that journal by Tewari et al. (Actually, we are having a hard time with the results of the study itself too.) … READ MORE …

The role of radical prostatectomy in older males with high-risk prostate cancer

Data reported earlier this year from the PIVOT study and separately from the long-term Scandinavian study have shown that the surgical treatment of prostate cancer in the patients enrolled in these trials showed no median prostate-cancer specific or overall survival benefit compared to watchful waiting in patients of > 65 years of age. … READ MORE …

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