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It has been well understood for years that biochemical recurrence (BCR) after radical prostatectomy does not always translate into systemic progression or necessarily lead to prostate cancer metastasis and death. The “natural history” of BCR is actually very variable.
Filed under: Living with Prostate Cancer, Management | Tagged: biochemical recurrence, natural history, outcome, prostatectomy, surgery | Leave a Comment »
A study reported this week in the Archives of Internal Medicine addresses the impact of biochemical recurrence on risk for prostate cancer-specific mortality (PCSM) among a cohort of more than 1,000 US veterans initially diagnosed and treated between 1991 and 1995.
Filed under: Living with Prostate Cancer, Management | Tagged: biochemical recurrence, long-term, outcome, radical prostatectomy, radiotherapy, veteran | 7 Comments »
Biochemical failure (also known as biochemical recurrence) after first-line treatment for prostate cancer is assessed based on a rising PSA level. This is a relatively common event and can happen shortly after first line treatment or many years later. The problem is that we really don’t know how important biochemical recurrence is in an individual [...]
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, comorbidity, Management, risk, survival | Leave a Comment »
A recent report in Cancer again seems to suggest that men with prostate cancer treated by radical prostatectomy (RP) who have a long time to biochemical recurrence (BCR) or a long PSA doubling time after BCR may have no higher overall risk of death than men who have no BCR at all.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, mortality, PSA doubling time, radical prostatectomy | 1 Comment »
In today’s new reports we summarize information from recent papers dealing with: Apical biopsy cores in initial diagnosis of prostate cancer Imaging studies in the initial work-up of newly diagnosed patients Intrafascial dissection of peri-prostatic tissue during laparoscopic surgery Similarity of short-term rates of biochemical recurrence after open surgery or RALP Does how we define [...]
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: apex, biochemical recurrence, biopsy, Diagnosis, dissection, imaging, intrafascial, open, RALP, risk, robot-assisted, surgery, work-up | 1 Comment »
Researchers associated with the Duke Prostate Cancer have re-calibrated an older nomogram (used to predict the likelihood of biochemical recurrence after a radical prostatectomy or RP). The revised nomogram is now capable of predicting not only biochemical recurrence but also the much more clinically significant risk for an aggressive recurrence — in which the post-surgical [...]
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: aggressive, biochemical recurrence, PSA doubling time, PSADT, radical prostatectomy, surgery | Leave a Comment »
Today’s prostate cancer news report deals with: A recent review of appropriate penile rehabilitation strategies Management of biochemical recurrence after first-line treatment failure Initial use of hormone therapy by French clinicians
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, hormone therapy, penile rehabilitation, radiation therapy, surgery | Leave a Comment »
We have reported separately on a study of the long-term durability of erectile function following brachytherapy using permanent seed implantation. Other reports today address: Literacy levels and prostate cancer communication Antiperspirant use as a possible cause of prostate (and breast) cancer A gene-based tool to predict prostate cancer risk Drugs in development for prostate cancer [...]
Filed under: Diagnosis, Drugs in development, Living with Prostate Cancer, Management, Prevention, Risk, Treatment | Tagged: allele, antiperspirant, biochemical recurrence, cause, communication, Diagnosis, Literacy, Prevention, PSA velocity, risk, salvage radical prostatectomy, tool | Leave a Comment »
Comment on an article on PSA velocity and prediction of biopsy outcomes has been provided separately. Today’s other news includes reports on: Pathological outcomes and criteria for active surveillance protocols Outcomes to permanent seed implant brachytherapy: age does not affect outcome Vacuum erectile devices and their value in post-prostatectomy erectile dysfunction Biochemical recurrence post-prostatectomy and [...]
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: active surveillance, age, biochemical recurrence, brachytherapy, hormone therapy, outcomes, pathology, vacuum erectile devices, VED | Leave a Comment »
It has long been known that men with apparently localized prostate cancer can relapse many years after radical prostatectomy and/or other forms of treatment that appear to have been curative. A new study from researchers at the University of Washington appears to throw some more light on why this may occur.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence, disseminated tumor cells, DTC | 11 Comments »
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