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An article just published by Grimm et al. in a supplement to BJU International argues (quite persuasively) that low-dose brachytherapy is the best form of treatment for men with low-risk prostate cancer.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: brachytherapy, comparative, low risk, low-dose, outcome | 1 Comment »
An analysis of data on treatment of nearly 137,500 men treated for prostate cancer between 1991 and 2007 has suggested that permanent seed brachytherapy may be safer, less costly, and at least as effective as any other widely available form of first-line therapy for men with low- and intermediate-risk prostate cancer.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, complications, cost, external beam, first line, radiation, radical prostatectomy, Treatment | 3 Comments »
A media release issued yesterday by ASTRO reads as follows:
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, efficacy, outcome, PBRT, proton beam, radiation therapy, safety | 5 Comments »
A new article in the journal Anticancer Research suggests that patients had greater satisfaction after modern forms of external beam radiation therapy (EBRT) than after some other standard forms of first-line treatment. Of course the absolute truth of this conclusion may be affected by the details of the study.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, external beam, hormone therapy, outcome, patient, radiation therapy, satisfaction, surgery | 1 Comment »
A newly published report in the Journal of the American Medical Association provides data (from two large cohorts of patients) on the quality of sexual function among men undergoing first-line treatment for localized prostate cancer.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: brachytherapy, external beam radiation therapy, post-treatment, prediction, radical prostatectomy, sexual function | 3 Comments »
For readers who are “into” the technical details, the American College of Radiology (ACR) has just updated the ACR Appropriateness Criteria® for the use of radiation therapy in the management of locally advanced (high risk) prostate cancer.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, EBR, external beam radiation therapy | Leave a Comment »
It has long been understood that erectile function after first-line treatment for localized prostate cancer is affected by (a) erectile function before treatment and (b) elapsed time after treatment. However, the available data offering a careful analysis of the chronology of erectile function after first-line treatment of localized prostate cancer has been limited.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, erectile dysfunction, erectile function, time | Leave a Comment »
The addition of androgen deprivation therapy (ADT) to radiation therapy for men with localized prostate cancer is common. It may be used to reduce the size of the prostate prior to brachytherapy or for longer periods in men with higher risk disease to extend survival (which has been demonstrated in large-scale, randomized, multi-center clinical trials).
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: ADT, androgen deprivation therapy, brachytherapy, cardiovascular disease, history, mortality, radiation, risk | 4 Comments »
A new retrospective analysis of data from > 2,300 patients suggests that African-American men are a greater risk for biochemical disease recurrence after brachytherapy alone than Hispanics or Caucasian men, but
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: African American, brachytherapy, mortality, outcome, race, recurrence | 1 Comment »
The recently published long-term results of RTOG 98-05 illustrate at least one way in which we can start to get better insight into the effectiveness and safety of new forms of treatment for localized prostate cancer as compared to older forms of treatment — without having to conduct complex and socially difficult randomized clinical trials.
Filed under: Management, Treatment | Tagged: brachytherapy, comparative, outcomes, RTOG 98-05 | 1 Comment »
It would be all too easy to get the idea — from the title and abstract of a recently published study — that proton beam radiation therapy (PBRT) was more effective than permanent seed brachytherapy in the treatment of men with low- and some intermediate-risk prostate cancers. This would be a very inappropriate conclusion.
Filed under: Management, Treatment | Tagged: beam, brachytherapy, comparison, EBRT, external, outcome, PBRT, proton, radiation therapy | 4 Comments »
The Johns Hopkins Health Alerts yesterday issued a new summary of the up- and the downsides of the four “standard” treatments for localized prostate cancer: active surveillance, radical surgery, external beam radiation therapy, and brachytherapy (with permanent seed implantation).
Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: active surveillance, brachytherapy, cons, external beam radiation therapy, pros, surgery | 4 Comments »
The Surgical Prostatectomy versus Interstitial Radiation Intervention Trial or SPIRIT was a Phase III, partially randomized clinical trial, conducted in the U.S.A. and Canada, and designed to compare radical prostatectomy (RP) and brachytherapy (BT) as first-line treatments for men with localized prostate cancer.
Filed under: Management, Treatment | Tagged: brachytherapy, HRQOL, localized, outcome, quality of life, radical prostatectomy, SPIRIT | Leave a Comment »
Apparently the German health system is to initiate a large trial to investigate the comparative effectiveness of four different treatments for men initially diagnosed with low-risk prostate cancer, starting this year.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: active surveillance, brachytherapy, comparative effectiveness, external beam radiation therapy, German, radical prostatectomy | Leave a Comment »
The American College of Radiology (ACR) and the American Society for Radiation Oncology (ASTRO) have jointly issued a new guidance document on the treatment of prostate cancer with permanent radioactive “seed” implants inserted through the perineum.
Filed under: Management, Treatment | Tagged: brachytherapy, guideline, Treatment | 4 Comments »
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