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A new paper in BJU International offers an analysis of data on the effectiveness and safety of focal cryotherapy (partial cryoablation of the prostate) as a first-line treatment for localized prostate cancer from the national Cryo On-Line Database (COLD) registry collected between 1997 and 2007.
Filed under: Management, Treatment | Tagged: COLD registry, cryotherapy, focal, outcome | Leave a Comment »
In a new paper just published on-line in the Journal of Urology, Kapoor et al. have provided data on trends in the utilization of various major types of treatment for the management of localized prostate cancer among Medicare beneficiaries in the USA between 2006 and 2008.
Filed under: Management, Treatment | Tagged: beneficiary, cryotherapy, Medicare, radiation, surgery, Treatment, utilization | Leave a Comment »
Based on data collected in the Cryo On-Line Database (COLD), Dhar et al. have just published an analysis of data from a total of 860 men, all over 75 years of age, who were treated with whole-gland cryoablation for clinically localized prostate cancer at times dating back to at least 1995.
Filed under: Diagnosis, Management, Risk, Uncategorized | Tagged: croablation, cryotherapy, elderly, outcome, risk, whole-gland | 1 Comment »
Two recent papers from a clinical research team at the University of Western Ontario in Canada have offered us insights into the appropriate usage of cryoablation as salvage therapy for men with progressive (recurrent) prostate cancer after first-line treatment for localized and locally advanced prostate cancer.
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: cryotherapy, outcome, prognosis, salvage | Leave a Comment »
We really have no idea what the “best” way is to treat men with progressive disease after first-line radiation therapy.
Filed under: Uncategorized | Tagged: cryotherapy, outcome, progression, radiation, salvage | 3 Comments »
A South Korean research team has just published data from a small, prospective, case-matched study comparing outcomes after cryotherapy + androgen deprivation therapy (CT + ADT) to outcomes after three-dimensional conformal radiation therapy + androgen deprivation (3D-CRT + ADT) in patients with high-risk prostate cancer.
Filed under: Management, Treatment | Tagged: "high risk", 3D-CRT, ADT, androgen deprivation therapy, conformation-beam, cryotherapy, outcome, radiation, three-dimensional | Leave a Comment »
There are several interesting new publications worth commenting on this morning — all in the evolving research field as opposed to current clinical practice: Angiogenic effect of a specific statin on prostate cancer development Synergistic impact of calcitriol on cryotherapy Hybrid imaging techniques and prostate cancer GTI-2040 in treatment of CRPC
Filed under: Drugs in development, Management, Risk, Treatment | Tagged: angiogenesis, calcitriol, cryotherapy, GTI-2040, hybrid, imaging, statin, synergy | Leave a Comment »
In a newly published report, a team of clinicians from Columbia University Medical Center has provided data on the 10-year follow-up of a small group of patients treated with salvage or primary cryotherapy for prostate cancer.
Filed under: Management, Treatment | Tagged: cryotherapy, outcomes | Leave a Comment »
One of the problems of first-line radiation therapy is how to treat patients with a rising PSA (biochemical relapse) after it becomes clear that the rise in PSA is not simply a “biochemical bounce” in the PSA.
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: cryotherapy, outcome, prognosis, salvage | Leave a Comment »
Data to be published in the May 2010 issue of the Journal of Urology are going to make a lot of urologists rather less than happy about the implications for the use of radical prostatectomy as first-line treatment for prostate cancer.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: brachytherapy, comparison, cryotherapy, HRQOL, outcome, quality of life, radical prostatectomy, RALP, RP | Leave a Comment »
News reports over the weekend included: Various review articles dealing with such matters as Gleason grading, numbers of cores taken at biopsy, the need for lymph node dissection, surgical technique and surgical margin control, and cryotherapy The effect of a water extract of white cocoa tea on prostate cancer cells in vitro and in a [...]
Filed under: Diagnosis, Management, Treatment | Tagged: biopsy, cryotherapy, Gleason grading, lymph node dissection, surgical margins, surgical technique, white cocoa tea | Leave a Comment »
Earlier this year we reported the initial results of a truly randomized Canadian trial of cryotherapy vs. external beam radiation therapy (EBRT) for the treatment of localized prostate cancer. The same group of authors have now reported follow-up data on quality of life.
Filed under: Management, Treatment | Tagged: cryoablation, cryotherapy, EBRT, external beam radiation therapy, randomized, trial | 2 Comments »
A recent publication has correlated nadir post-cryoablation PSA levels (i.e., the lowest PSA level achieved by the patient after treatment) with long-term biochemical disease-free survival in a risk-stratified cohort of patients with prostate cancer treated with cryoablation.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: biochemical recurrence-free, cryoablation, cryotherapy, first line, survival | Leave a Comment »
Today’s prostate cancer news reports cover items on: Assessment of quality of life after radical prostatectomy Permanent seed brachytherapy in treatment of localized disease Cryotherapy in treatment of patients with Gleason 8-10 localized disease Actonel and/or estradiol in prevention of SREs
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: Actonel, brachytherapy, cryotherapy, estradiol, Gleason score, outcome, permanent, quality of life, risedronate, seed, survey | Leave a Comment »
Today’s news reports include discussion of items on: Prostate cancer risk awareness Improving cryotherapy technique with 3D ultrasound Interposition (“sural”) nerve grafting Post-brachytherapy “PSA bounce” The potential of targeted, peptide-linked, α-emitting radioisotopes
Filed under: Diagnosis, Drugs in development, Management, Prevention, Risk, Treatment | Tagged: African American, awareness, brachytherapy, cryotherapy, Hispanic, interposition, nerve grafting, PSA bounce, radiopeptides, risk, sural, targeted, therapy | 3 Comments »
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