mpMRI scans before biopsy, mpMRI-guided biopsies recommended in UK

An article in The Daily Telegraph in the UK this morning addresses a variety of issues related to the difficulties associated with the use of TRUS-guided prostate biopsy to diagnose localized and locally advanced prostate cancer. … READ MORE …

Vasectomy and risk for prostate cancer all over again

Over the years there has been controversy as to the existence of an association between vasectomy and risk for prostate cancer. A new set of data from a large, long-term study, to be presented at the upcoming annual meeting of the American Society of Clinical Oncology, has shown that there is, indeed, such a risk — but it is specific to high-risk prostate cancer. … READ MORE …

Statin use before diagnosis associated with less risk of prostate cancer-specific mortality

According to an article just published on line in Prostate, taking statins before a diagnosis of prostate cancer lowers risk for prostate cancer-specific mortality (but does not lower risk for progression/recurrence of prostate cancer after first-line treatment). … READ MORE …

mpMRI in diagnosis and management of prostate cancer tomorrow

A new review article in Oncology discusses the potential of multiparametric magnetic resonance imaging (mpMRI) in the diagnosis and management of prostate cancer, and will be useful reading for many advocates and support group leaders. … READ MORE …

Lots of new tests, but will they really make a difference?

An article by Andrew Pollack in Tuesday’s New York Times is entitled “New prostate cancer tests could reduce false alarms.” However, we encourage our readers to scrutinize this article with care. It is full of “may”s, “could”s, “might”s, and “if”s (as one should expect). … READ MORE …

Tea, coffee consumption and risk for prostate cancer diagnosis

So that we are clear, we really dislike studies like this that appear to suggest that one particular type of food or drink is “associated” with higher or lower risk for a specific disorder. While they may have some level of scientific interest, their clinical value is certainly limited and may be negligible … yet they get a lot of media coverage. … READ MORE …

How to cut your overall risk for all cancer by 51 percent, BUT …

There has been significant media coverage of a recent article in the journal Circulation. The article reports that individuals enrolled in the Atherosclerosis Risk in Communities (ARIC) study were able to cut their overall risk for cancer by 51 percent. … READ MORE …

The developing Cancer Survival Query System (CSQS) and its application to prostate cancer

Just over a month ago we mentioned the CSQS in commenting on a Swedish paper (by Eloranta et al.) that dealt with prediction of the “crude” or “real world” probability of death from prostate cancer (as opposed to potential, competing causes of death). … READ MORE …

Is active surveillance reasonable for some men with Gleason 7 prostate cancer?

There has long been a question about the potential role of active surveillance as a management strategy for men diagnosed with prostate cancer and with a Gleason score of 3 + 4 = 7. … READ MORE …

Active surveillance and racial difference in risk

A new article in Urology (“the Gold journal”) suggests that African American men diagnosed with low-risk forms of prostate cancer may need to meet more stringent criteria than Caucasian Americans if they are to be appropriately managed on active surveillance protocols. Why? Because they appear to be at higher risk for disease progression. … READ MORE …

One patient’s personal journey to active surveillance

There was an interesting personal story in Monday’s Washington Post (as told by the patient’s wife) of one man’s journey toward the decision to manage his prostate cancer with active surveillance. … READ MORE …

Elderly and black males at greater risk for aggressive disease?

An epidemiological analysis of data from the Surveillance, Epidemiology, and End Results (SEER) database shows that older and black males have higher risk for intermediate- and high-risk prostate cancer, … READ MORE …

What happened early this morning at the GU Cancers Symposium

So … as a couple of readers have already realized … the sheer quantity of new and interesting data at the meeting is enormous, and your reporter is going to have to select what he tries to covers with care, ‘cos there’s no way to cover it all! … READ MORE …

The practical utility of prostate cancer survival and mortality data for clinicians and patients

Imagine that you are 65 years of age and have just been diagnosed with intermediate-risk prostate cancer (clinical stage T1c; PSA 3.7 ng/ml; Gleason 3 + 4 = 7; with 3/12 biopsy cores positive for cancer, all in the left lobe). You understand quickly that this places you at some risk for progressive disease, and perhaps even for prostate cancer-specific mortality. … READ MORE …

Is race a factor in exercise and prostate cancer prevention?

We have known for some time that regular exercise may lower risk for prostate cancer. Indeed, a study by Clarke and Whittemore published in 2000 suggested that men who take little to no exercise may be 1.7 times more likely to be diagnosed with prostate cancer than those who exercise with a degree of regularity. … READ MORE …

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