The end of EPCA-1 and EPCA-2 as a diagnostic/prognostic test for prostate cancer

According to a news report this morning, a paper originally published in Urology (the Gold Journal) in 2007, and that reported that “early prostate cancer antigen” (EPCA) had the potential to replace the PSA test, has been retracted by the authors.

Just more déjâ vu all over again

So we might as well acknowledge that the New Year is going to continue where the old year left off when it comes to the issue of testing (“screening”) men for risk of prostate cancer.

The new NCCN patient guidelines — a great improvement over last time

We have now had the chance to look carefully through the new, patient-specific guidelines on prostate cancer issued by the National Comprehensive Cancer Network (NCCN) just before the Holidays. They are not perfect, but they are certainly a vast improvement over the NCCN’s first attempt.

Prostate cancer risk: an investigative journalist’s tale

When Paul VanDervelder was told his PSA had spiked, he did what many men do. He panicked! But then he did what he was trained to do as an investigative journalist. He investigated.

Prostate cancer screening (in Germany): curative or harmful?

The debate over the merits and risks of widespread screening for prostate cancer using the PSA test is hardly confined to the USA. A new article (in German) in the journal Urologie A addresses exactly the same issues as have recently received so much attention here in the States.

AUA issues full, formal comments on USPSTF draft recommendation

On November 8, the American Urological Asociation (AUA) issued its full, formal comment letter on the US Preventive Services Task Force (USPSTF)’s draft recommendation of a “D” grade for the use of PSA screening in healthy men with no symptoms of prostate cancer. The AUA also issued a formal statement for the media.

A medical oncologist’s views on the USPSTF draft recommendations

An article by a highly regarded specialist in medical oncology in the most recent issue of The ASCO Post discusses recent recommendations from the U.S. Preventive Services Task Force (USPSTF).

Another investigational test may refine data on need for prostate biopsy

A newly published paper  in the Journal of Urology describes a multi-center, prospective study of the potential of the investigational, urine-based, ProCaM™ assay as a test to offer improved evaluation of the need for prostate biopsy among men with an initial total serum PSA level between 2 and 10 ng/ml.

3 Tesla MRI imaging and the diagnosis of localized prostate cancer

It has been noted previously in this blog that we are improving our ability to accurately identify localized prostate cancer using several types of imaging technology.

Can Sebelius actually NOT cover the costs of PSA testing for Medicare patients?

A key concern associated with the USPSTF recommendation that widespread “screening” of uninformed men be eliminated is that this recommendation would lead to non-coverage of PSA testing in otherwise healthy men.

One expert clinician’s very public opinion about the USPSTF recommendation

Readers might want to read an article by Ralph de Vere White, MD, the Director of the UC Davis Cancer Center at the University of California Davis in Sacramento, California. Dr. de Vere White is a respected urologic oncologist known to have a strong commitment to shared decision making with patients on issues of cancer risk [...]

The USPSTF recommendation … How to comment

The following statement about how to comment on the USPSTF recommendation that uninformed, mass screening of men for risk of prostate cancer is not supported by available evidence can be found on the USPSTF web site:

USPSTF “forced” to release PSA recommendations earlier than expected

The U.S. Preventive Services Task Force (USPSTF) — after previously stating that it would be releasing its new recommendations about PSA testing for risk of prostate cancer on Tuesday next week — has been pressured (by a variety of organizations, and by the media) to release its draft recommendation today.

USPSTF advises against all PSA screening in healthy men

According to an article in today’s New York Times, the United States Preventive Services Task Force (USPSTF) has chosen to advise against routine use of the PSA test to screen healthy men for prostate cancer because “the test does not save lives and often leads to more tests and treatments that needlessly cause pain, impotence [...]

Excess deaths among some older men with prostate cancer

A population-based analysis of mortality data for men diagnosed with prostate cancer from three European nations suggests that “a small but important group of older patients” initially present with late stage prostate cancer and die rapidly as a consequence.

Follow

Get every new post delivered to your Inbox.

Join 332 other followers