BMJ clinical review discourages widespread prostate cancer screening

A clinical review in this week’s issue of the British Medical Journal (BMJ) states clearly that “Prostate cancer screening with the PSA blood test results in at most a small reduction in prostate cancer mortality and leads to considerable diagnostic and treatment related harms” and that “Physicians should recommend against PSA screening for prostate cancer.” … READ MORE …

Hyping the risk for prostate cancer … to what end?

According to a media release issued by Cancer Research UK a few days ago, “Boys born in 2015 will have almost three times the risk of being diagnosed with prostate cancer at some point during their lives than those born in 1990.” … READ MORE …

White blood cell density and risk for prostate cancer

A recent Japanese paper has suggested that a low white blood cell (neutrophil) count may be an independent predictor of risk for a positive biopsy and a diagnosis of prostate cancer. … READ MORE …

The state of prostate cancer management in Senegal, West Africa

We hear remarkably little about what is happening in the diagnosis and treatment of prostate cancer from developing countries in Africa and elsewhere, so a recent paper in Progrès en Urologie is of some interest. Although the full text is in French, the abstract is available in English too. … READ MORE …

Age, hair loss, and risk for prostate cancer diagnosis

An excellent commentary on the NHS Choices web site addresses an article by an Australian research team showing that men who show signs of baldness by age 40 are at heightened risk for a diagnosis of prostate cancer, but that this is not the case at older ages. The risk of having prostate cancer at > 76 years old was about 15 percent in this study, regardless of hair loss at 40. … READ MORE …

Of cow’s milk, doughnuts, fried chicken, and other important food groups

Two recent articles have linked certain dietary habits to risk for development of prostate cancer. The degree to which one feels that these dietary habits may be “proven” to increase risk for prostate cancer is probably going to be debatable; the existence of a potential link is certainly clear. … READ MORE …

Diagnosis of prostate cancer in UK projected to be more common

According to a report in today’s Daily Telegraph, Cancer UK is projecting a significant increase in risk for a diagnosis of prostate cancer in the United Kingdom over the next 50 to 60 years. … READ MORE …

Over-inflation of the significance of PSA velocity in Kaiser paper

We still haven’t been able to see the full text of the article by Wallner et al. (reported yesterday) suggesting that PSA velocity was as good or better than a single PSA data point in predicting risk for prostate cancer — and for aggressive types of prostate cancer in particular. However, … READ MORE …

PSA velocity and risk for clinically significant prostate cancer

Analysis of data from > 200,000 men, all enrolled in a large California managed care health plan, appears to offer us some “insight into the usefulness of PSA velocity as a detection marker for aggressive prostate cancer.” … READ MORE …

DRE is still a key diagnostic tool in assessing risk for prostate cancer

A new study just published in the Canadian Journal of Urology has reminded us of the importance of the digital rectal emamination (DRE) in the initial diagnosis of prostate cancer. … READ MORE …

Diet, nutrition, and primary and secondary prostate cancer prevention

Primary prostate cancer prevention strategies are ones designed to minimize the risk of getting this cancer in the first place. Secondary prevention strategies are those designed to minimize the risk for disease progression after diagnosis (whether one actually has any form of treatment or one simply follows some form of monitoring strategy). … READ MORE …

OPKO Health, OURLab, and the 4Kscore test for prostate cancer risk

According to a media release on the company’s web site, OPKO Health has completed the acquisition of Prost-Data, Inc. (otherwise known to many prostate cancer patients and support group leaders – as well as their urologists — as Jonathon Oppenheimer’s independent uropathology company OURLab). … READ MORE …

Test your knowledge on the diagnosis and staging of prostate cancer

Support group leaders and other prostate cancer educators may wish to test their knowledge on the diagnosis and staging of prostate cancer by reading through the set of 29 slides prepared by Kleynberg and Gross and just made available on the Medscape web site.

Apparently “Gandalf” has localized prostate cancer

According to a recent report in The Daily Mail (one of our favorite English newspapers), Sir Ian McKellen, the actor who plays the wizard Gandalf in the Lord of the Rings movies, as well as the recently opened movie of The Hobbit, has had localized prostate cancer for 6 or 7 years. … READ MORE …

MRI/ultrasound fusion prostate biopsy in diagnosis of prostate cancer

A new paper in this month’s Journal of Urology has suggested that biopsy of lesions identified using a 3.0 T MRI scan and targeted for biopsy using an MRI/ultrasound image fusion technique may be able to significantly improve the probability of detection of clinically relevant prostate cancers in an office setting. … READ MORE …

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