Prostate cancer patients on statins have better outcomes after radiotherapy

There is an increasing range of evidence to suggest that men who are on long-term statin therapy (with drugs like simvastatin, atorvastatin/Lipitor, or rosuvastatin/Crestor) are at lower risk for prostate cancer and do better than average in terms of treatment outcome if they are diagnosed with prostate cancer.

Chronic fatigue after first-line therapy for localized prostate cancer

There are few good data on the occurrence of chronic fatigue after first-line treatment of localized prostate cancer.

Decline in sexual function after radiation therapy for prostate cancer

A newly published report suggests that sexual function does indeed decline after external beam radiation therapy (EBRT) for prostate cancer — but only over the first 2 years post-treatment.

Prostate cancer news reports: Wednesday, January 20, 2010

In today’s news reports we comment on three different articles dealing with radiotherapy in first-line treatment for localized prostate cancer: Iodine-125-based brachytherapy without adjuvant hormone therapy or EBRT in younger males Comparative outcomes of brachytherapy patients of 60 and younger and > 60 years of age Radiation toxicities after EBRT in men who have had [...]

Hormones + brachytherapy + EBRT: more than we need?

A paper in press in the Journal of Urology has suggested that, for patients with intermediate-risk prostate cancer who elect treatment with a combination of standard (low dose) brachytherapy and external beam radiation therapy (EBRT), the addition of hormone therapy adds little in terms of clinical benefit.

Long-term follow-up of patients needing post-RP salvage radiation

A long-term study from the Mayo Clinic reports a low incidence of complications (other than erectile dysfunction) following salvage radiotherapy for men with prostate cancer recurrence after an initial radical prostatectomy.

QOL after cryotherapy vs. EBRT

Earlier this year we reported the initial results of a truly randomized Canadian trial of cryotherapy vs. external beam radiation therapy (EBRT) for the treatment of localized prostate cancer. The same group of authors have now reported follow-up data on quality of life.

Prostate cancer news reports: Tuesday, July 21, 2009

In today’s news reports we comment on studies dealing with: PSA level, body mass index, risk, and outcomes External beam radiotherapy in treatment of Japanese patients An endorectal balloon to prevent anal/rectal side effects of radiation? The optimal period of neoadjuvant hormone therapy prior to radiation therapy

Prostate cancer news reports: Saturday, July 18, 2009

In today’s news reports you will find items on: Obesity and PSA levels Outcomes after external beam radiation therapy Mitoxantrone + predisone after taxotere failure

Additional evidence of the value of brachytherapy + EBRT + ADT in high-risk patients

Earlier today we reported data from a series of patients treated by Stock et al. with brachytherapy + external beam radiation therapy (EBRT) + androgen deprivation therapy (ADT). According to a HealthDay report published in Forbes magazine, a second paper appears to endorse the findings of Stock and his colleagues.

Combined brachytherapy, EBRT, and ADT for high-risk disease

Eight-year outcome data are now available for patients with Gleason score 8-10 prostate cancer treated with brachytherapy, external beam radiotherapy (EBRT), and androgen deprivation therapy (ADT).

Prostate cancer radiotherapy in men on warfarin or Plavix

A recent study has assessed the risk of bleeding as a consequence of radiation therapy for localized prostate cancer in men being treated with anticoagulants .

Prostate cancer news reports: Friday, June 26, 2009

Today’s prostate cancer news report summary includes items dealing with: The epigenetics of prostate cancer and their potential importance Selenium + vitamin E + lycopene (in mice) Gleason 7: 4 + 3 versus 3 + 4 — it’s important Proton beam radiotherapy — a topical review EBRT + low dose, permanent seed brachytherapy

Prostate cancer news reports: Friday, June 12, 2009

Todays news reports adddress: Surgeon and hospital volume and outcomes to radical prostatectomy Adverse events associated with the use of hypofractionated, dose-escalated, IMRT Quality of sexual function after external beam radiation therapy Percentage of positive biopsy cores and response to first-line hormone therapy

The Thursday morning news reports: January 8, 2009

This morning’s news reports address: Prostate cancer risk and obesity (again) Italian experience with HIFU at a median follow-up of about 2 years The prognostic value of a 5-year PSA value <0.2 ng/ml in men treated with brachytherapy (with or without EBRT and/or hormones) Proposed European guidelines on the need to remove the seminal vesicles [...]

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