Manserin as possible marker of prostate cancer progression

“Manserin” is a novel peptide originally derived from a larger secretory protein called secretogranin II. A newly published paper suggests that expression of manserin in human prostate cancer tissues may correlate with risk for clinically significant and progressive forms of prostate cancer.

UK includes prostate cancer in new “stratified medicine” pilot program

According to a report in the Science section of the Financial Times, “the world’s first nationwide genetic testing programme for cancer patients goes into action in the UK next month, with support from the public, private and charitable ­sectors.”

5α-Reductase-III and its potential in prevention/treatment of prostate cancer

There are in fact three so-called “isozymes” (slightly different versions) of the human enzyme 5α-steroid reductase. The activity of 5α-reductase-II can be affected by the 5α-reductase inhibitor (5-ARI) finasteride (Proscar); the activity of 5α-reductase-I and -II can be affected by the 5-ARI dutasteride (Avodart), but

Perhaps all too much FUS about something …

As usual, some of our friends in the media are over-hyping a recent publication about the possible effects of a protein called FUS/TLS in the progression of prostate cancer.

siRNA, NMD, and tumor antigen expression in cancer

A research team at the University of Miami has come up with an innovative new method that (please note the emphasis) might offer a completely new way to eliminate remaining cancer cells in patients with prostate and other types of cancer after first-line therapy.

Prostate cancer news reports: Friday, May 22, 2009

Today’s news reports cover items on: Gene expression and prostate cancer progression Risk of complications from in-office prostate biopsy Post-RALP voiding function Urinary toxicities after IMRT-SIB Drugs in development for CRPC

Prostate cancer news reports: Friday, May 15, 2009

In today’s news reports we discuss: Genetic abnormalities and intermediate risk prostate cancer Ginger tablets to prevent chemotherapy-induced nausea Ixabebilone + mitoxantrone in patients after Taxotere

The early weekend news report: January 17, 2009

There are just two notable reports in today’s early news: On the potential of PMS2 as a prostate cancer marker On age-related cancer outcomes in Europe

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