30 years follow-up of men with initially untreated, localized prostate cancer

A new article in European Urology offers interesting data on the natural history of localized prostate cancer, based on a cohort of 200+ Swedish patients followed for > 30 years. It is important to note immediately that none of these men was originally diagnosed in the PSA era. They all had some form of symptomatic disease at diagnosis. … READ MORE …

Orgasmic function is not the same as sexual function: what are we really being told?

We are having a hard time with a media release issued yesterday by BJU International in relation to a study just published in that journal by Tewari et al. (Actually, we are having a hard time with the results of the study itself too.) … READ MORE …

Survey suggests high level of long-term side effects after treatment for prostate cancer

According to new data presented at the Frontiers in Cancer Prevention Research meeting ongoing this week in Boston, MA, some 70 percent of prostate cancer patients participating in a survey in Michigan reported long-term, treatment-related, adverse effects after first-line treatment with surgery or radiation therapy. … READ MORE …

PSA monitoring after prostate cancer surgery: how long is long enough?

A paper currently “in press” in the Journal of Urology suggests that annual PSA testing “may be safely discontinued after 10 years for men with a prostatectomy Gleason score 6 or less and/or limited life expectancy.” … READ MORE …

Delayed follow-up care of men with a high PSA found to be common

For any man with a first-time PSA level > 10 ng/ml, there is significant risk for prostate cancer, and early follow-up care — including a repeat PSA test and potentially a biopsy — is probably a priority unless the patient has a life expectancy of 10 years or less. … READ MORE …

Follow-up after finding of “atypia” on initial prostate biopsy

It has long been understood that a finding of “atypia” (atypical small acinar proliferation) on an initial biopsy of the prostate is associated with an increased risk for prostate cancer, and a repeat biopsy is normally recommended for any patient with an initial finding of atypia. … READ MORE …

Evolving “best practices” in the application of active surveillance

A new paper based on the cohort of patients being followed with active surveillance (AS) at Memorial Sloan-Kettering Cancer Center (MSKCC) has added to our understanding of the potentially optimal management of patients on AS. … READ MORE …

Follow-up PSA testing after surgery for low-risk prostate cancer

One of our regular readers has suggested we comment on a recent paper questioning the need for annual, lifelong PSA testing after radical prostatectomy for patients treated for low-risk prostate cancer. … READ MORE …

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