Korean study says that HIFU “does not provide effective oncologic outcomes”

A new paper by clinical researchers in Korea has concluded that treatment with high-intensity focused ultrasound (HIFU) “does not provide effective oncologic outcomes even in low risk patients with prostate cancer as well as in the intermediate or high risk groups,” but does have a low associated incidence of treatment complications.

New data suggest that salvage HIFU after EBRT is “a high-risk procedure”

A new article reports data from two centers on experience with whole-gland high-intensity focused ultrasound (HIFU) salvage therapy for local recurrence following external beam radiation therapy (EBRT).

Further experience with salvage HIFU after first-line EBRT

A second, small study has now offered additional data on clinical experience of the use of high-intensity focused ultrasound (HIFU) as a form of salvage therapy in men initially diagnosed with localized prostate cancer, but with a rising PSA after external beam radiation therapy (EBRT) as their first-line treatment.

Health-related QOL after salvage HIFU for recurrent, localized prostate cancer

Men with locally recurrent prostate cancer after first-line external beam radiation therapy (EBRT) have historically had three options for second-line treatment: salvage radical prostatectomy, salvage cryoablation, and salvage brachytherapy.

Feasibility of focal HIFU: a pilot study with 10-year follow-up data

The potential of high-intensity focused ultrasound (HIFU) as a form of focal therapy for treatment of cancer isolated to a portion of the prostate as opposed to treatment of the entire prostate has been recognized for a considerable period of time. However, limited data are available so far on the outcomes of men treated with [...]

Apical prostate cancer and recurrence after HIFU

The presence of prostate cancer in the apex (the lowest tip) of the prostate is always a challenging aspect for treatment of localized prostate cancer, because this places the cancer close to the nerves that control erectile function (potency) and to the sphincter (valve) that controls urine flow.

Risk associated with rapid rise in PSA immediately following HIFU

An article in the April issue of Clinical Medical Insights: Oncology suggests that a rapid post-treatment increase in the PSA levels of men treated for localized prostate cancer with high-intensity focused ultrasound (HIFU) may indicate later risk for biochemical recurrence.

15 years of experience with HIFU using Ablatherm technology

A media release issued by EDAP TMS SA – the developer and distributor of the Ablatherm® technology used in high-intensity focused ultrasound (HIFU) treatment of men with prostate cancer – states that a review of 15 years experience with Ablatherm technology will be published in the June issue  of Current Urology Reports.

EBRT as salvage therapy for refractory or progressive prostate cancer post-HIFU

An early release paper in the Canadian Urological Association Journal offers information on a series of patients treated with external beam radiation therapy (EBRT) as salvage therapy after biochemical progression following high-intensity focused ultrasound (HIFU) as their first-line treatment.

HIFU as first-line treatment in 137 Japanese patients

Data from a series of Japanese patients continue to help us to understand the risks and benefits of first-line treatment with high-intensity focused ultrasound (HIFU) for men initially diagnosed with localized prostate cancer and followed for up to 7 years.

HIFU as first-line therapy in intermediate- and high-risk patients

A report from an Italian clinical research group has offered data from > 150 patients treated with high-intensity focused ultrasound (HIFU) with an average of > 5 years of follow-up.

Outcomes after HIFU and prognosis based on post-HIFU PSA nadir levels

A new analysis of data from the multi-center @-Registry of patients undergoing Ablatherm-based high-intensity focused ultrasound (HIFU) for the treatment of localized prostate cancer suggests that nadir levels of PSA post-treatment can be used to predict the probability of biochemical progression-free survival (bPFS) at 5 years of follow-up.

Focal (hemiablative) HIFU in the treatment of localized prostate cancer

To date there have been few data from well-documented, prospective series of patients receiving any form of focal therapy as treatment for localized prostate cancer, and the criteria for the appropriate clinical use of focal therapy are still a matter of considerable debate.

5-year outcomes data from a French series of HIFU patients

A new report from a French research team has provided detailed 5-year data on the oncological outcomes of a series of low- and intermediate-risk prostate cancer patients treated with high-intensity ultrasound (HIFU) using second-generation Ablatherem™ equipment.

An unenthusiastic review of HIFU in prostate cancer

The potential value of high-intensity focused ultrasound (HIFU) as a treatment for prostate cancer continues to foment controversy between its advocates and its detractors.

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