Prostate Cancer International is
for 2011 by Great NonProfits
Perspective Confidentiality Disclosure Reliability Courtesy
In the October issue of European Urology there was an interesting “consensus statement” about the role of radiation therapy as adjuvant or salvage therapy for men who are at significant risk for recurrence of their prostate cancer after first-line treatment with radical prostatectomy.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: "high risk", adjuvant, post-surgery, radiation therapy, salvage | 1 Comment »
In light of the publication this week of data by Warde et al. on external beam radiation therapy + lifelong total androgen deprivation (ADT) as a first-line treatment for high-risk, localized and locally advanced prostate cancer (click here for commentary), it is interesting to note an article from another research group outlining experience with a [...]
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: "high risk", localized, locally advanced, prostatectomy, robot-assisted | Leave a Comment »
The big news today is the publication, in The Lancet, of the interim results of the NCIC CTG PR.3/MRC UK PR07 trial, originally presented by Warde et al. at the annual meeting of the American Society for Clinical Oncology in June 2010 and then by Mason et al. at the annual meeting of the American [...]
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: "high risk", ADT, androgen deprivation therapy, EBRT, external beam radiation therapy, localized, locally advanced | Leave a Comment »
An article by Schmitges et al., originally published in Therapeutic Advances in Urology in August this year, has just been reproduced on the Medscape Oncology web site, where it is available in complete form.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: "high risk", surgery | 8 Comments »
Data reported earlier this year from the PIVOT study and separately from the long-term Scandinavian study have shown that the surgical treatment of prostate cancer in the patients enrolled in these trials showed no median prostate-cancer specific or overall survival benefit compared to watchful waiting in patients of > 65 years of age.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: "high risk", age, elderly, old, radical prostatectomy, RALP, robot-assisted | 2 Comments »
Back in June 2010, we reported on the initial results of SWOG 9921 — a trial that randomized 983 men with high-risk features at prostatectomy to receive adjuvant therapy with androgen deprivation (ADT) alone or in combination with mitoxantrone chemotherapy.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: "high risk", adjuvant, ADT, androgen deprivation therapy, surgery | 6 Comments »
Data from the Cleveland Clinic offer some insight into the medium- and long-term outcomes of a cohort of men initially diagnosed between January 1998 and June 2004 with high-risk, localized prostate cancer and treated by radical prostatectomy alone as their first-line therapy.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: "high risk", outcome, radical prostatectomy | 2 Comments »
The stream of information about long-term outcomes after brachytherapy continues with an article on 10-year outcomes of high-risk patients treated with brachytherapy, adjuvant external beam radiation, and adjuvant androgen deprivation (ADT).
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: "high risk", ADT, androgen deprivation, brachytherapy, external beam radiation therapy, localized, outcome | Leave a Comment »
As we reported at the time, at the annual meeting of the American Society for Clinical Oncology, in June this year, Warde et al. presented the initial survival data from a large, multi-center trial of androgen deprivation therapy (ADT) + radiation compared to ADT alone for patients with high-risk, localized prostate cancer.
Filed under: Management, Treatment | Tagged: "high risk", ADT, androgen deprivation therapy, localized, radiation | Leave a Comment »
For many years surgery was considered to be inappropriate for most men with locally advanced prostate cancer — most particularly those with positive lymph nodes (TxN1Mx) at the time of surgery.
Filed under: Diagnosis, Management, Treatment | Tagged: "high risk", localized, locally advanced, node-positive, surgery | Leave a Comment »
A South Korean research team has just published data from a small, prospective, case-matched study comparing outcomes after cryotherapy + androgen deprivation therapy (CT + ADT) to outcomes after three-dimensional conformal radiation therapy + androgen deprivation (3D-CRT + ADT) in patients with high-risk prostate cancer.
Filed under: Management, Treatment | Tagged: "high risk", 3D-CRT, ADT, androgen deprivation therapy, conformation-beam, cryotherapy, outcome, radiation, three-dimensional | Leave a Comment »
New data from a series of > 700 elderly patients with high-risk prostate cancer suggests that aggressive combination therapy for such men is associated with a reduced risk for prostate cancer-specific mortality.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: "high risk", ADT, androgen deprivation therapy, brachytherapy, elderly, external beam radiation therapy, mortality | Leave a Comment »
Results of a study (the GETUG 12 trial) presented today at the ASCO 2010 Genitourinary Cancer Symposium in San Francisco suggest that the addition of docetaxel-based chemotherapy to androgen deprivation and radiation therapy may impact biochemical recurrence of prostate cancer in high risk patients with localized disease — but it will take a while before [...]
Filed under: Uncategorized | Tagged: "high risk", docetaxel, localized disease | 1 Comment »
A newly published Italian study offers what we believe to be the first direct comparison of two “modern” types of external beam radiation therapy for the treatment of localized, high-risk prostate cancer. This is a relatively small trial, with relatively brief follow-up to date, but the results are nontheless interesting and important.
Filed under: Management, Treatment | Tagged: "high risk", external beam radiation, localized, randomized, trial | 2 Comments »
Search for new and
ongoing trials on the
CTAG PCa web site