Time to prove a treatment-related prostate cancer survival benefit

For most of the past 20 years it has generally been considered that it took 10 years to show that a new form of therapy was effective and safe in the treatment of localized prostate cancer. We may need to seriously re-assess that time period. … READ MORE …

Patient life expectancy and application of radical prostatectomy in Ontario, Canada

An interesting epidemiological study just published on line in the Journal of Urology suggests that urologic surgeons in Ontario, Canada, are rather good at at estimating which patients diagnosed with prostate cancer have a life expectancy of 10+ years, making them reasonable candidates for radical prostatectomy. … READ MORE …

Of cost, quality, and care for low-risk prostate cancer

A newly published study in the Annals of Internal Medicine has offered an analysis of the cost-effectiveness of “observation” as compared to immediate initial treatment for men diagnosed with low-risk, localized prostate cancer. … READ MORE …

Life expectancy ≤ 10 years and the risks associated with treatment

According to Reuters, a new article, forthcoming on line in the Annals of Internal Medicine, tells us (not too surprisingly) that, “Older men with other illnesses may not live long enough to benefit from aggressive prostate cancer treatments, such as prostate removal or radiation, and they’d have to live with their side effects.” … READ MORE …

“There’s more to life than death”

We strongly recommend to all our readers a commentary in this week’s New England Journal of Medicine by Drs. Pamela Hartzband and Jerome Groopman. It deals forcefully with distinction between “statistical proof” of the lack of value of PSA testing and the accuracy of that statistical proof as a basis for clinical decision-making. … READ MORE …

Potential years of life lost due to prostate cancer in the USA: 1972-2006

An analysis published by Kamel et al. in the Journal of Urology earlier this year offers an estimate of the potential years of life lost (PYLL) due to prostate cancer in seven 5-year periods between 1972 and 2006. (Prostate cancer was the most prevalent of several forms of urogenital cancer addressed in this report.) … READ MORE …

Active surveillance or immediate surgery for low-risk prostate cancer: let’s look at the math

A new study has attempted to calculate the impact of age, health status, and patient preference on the relative outcomes (and merits) of immediate surgery as compared to active surveillance for the management of low-risk prostate cancer. … READ MORE …

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