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Another newly published paper, this time in the British Journal of Urology, addresses issues related to cardiovascular disease and the treatment of prostate cancer.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: comorbidity, localized, regret | 1 Comment »
In light of the publication this week of data by Warde et al. on external beam radiation therapy + lifelong total androgen deprivation (ADT) as a first-line treatment for high-risk, localized and locally advanced prostate cancer (click here for commentary), it is interesting to note an article from another research group outlining experience with a [...]
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: "high risk", localized, locally advanced, prostatectomy, robot-assisted | Leave a Comment »
The big news today is the publication, in The Lancet, of the interim results of the NCIC CTG PR.3/MRC UK PR07 trial, originally presented by Warde et al. at the annual meeting of the American Society for Clinical Oncology in June 2010 and then by Mason et al. at the annual meeting of the American [...]
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: "high risk", ADT, androgen deprivation therapy, EBRT, external beam radiation therapy, localized, locally advanced | Leave a Comment »
The following article, by Ravinder Mohan, MD, PhD, is reproduced from the UroToday web site with kind permission of Dr. Mohan and the publishers of UroToday. We had previously commented on the original article, published last month in American Family Physician.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: decision-making, guidelines, localized, patient, patient-centered, Treatment | 5 Comments »
Every day across America and around the world, newly diagnosed patients are told they have “localized” prostate cancer … with the associated implication that this is a relatively “good thing” compared to a diagnosis of “advanced” prostate cancer. But what does “localized” prostate cancer really mean in individual cases?
Filed under: Diagnosis, Management, Risk | Tagged: category, definition, localized, sub-category | 4 Comments »
Two recent publications have offered evidence that, at 10 and 12 years of follow-up, the potential benefits of surgical treatment for low- and intermediate-risk prostate cancer did not include any impact on overall survival for men of 65 years of age or more at the time of surgery.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: benefit, complication, elderly, localized, outcome, over-treatment, risk, side effect | 2 Comments »
The presence of prostate cancer in the apex (the lowest tip) of the prostate is always a challenging aspect for treatment of localized prostate cancer, because this places the cancer close to the nerves that control erectile function (potency) and to the sphincter (valve) that controls urine flow.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: apex, HIFU, high-intensity focused ultrasound, localized, outcome, recurrence | 4 Comments »
An updated, systematic review just published in Annals of Internal Medicine states that it is impossible to come to any conclusions about the efficacy of radiation therapy compared with active surveillance or watchful waiting for the management of localized prostate cancer because of the absence of any high-quality, comparative data.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: benefit, comparative, localized, outcome, radiation | Leave a Comment »
An article by Crawford and Arangua on page 3 of the June issue of AUA News provides a series of “take home messages” for attendees of the annual meeting of the American Urological Association in Washington, DC, last month.
Filed under: Management, Treatment | Tagged: annual meeting, AUA, localized | 4 Comments »
In February this year we reported initial 4- and 5-year follow-up data from two US-based research teams on the use of stereotactic body radiation therapy (SBRT or CyberKnife radiation) as a treatment for prostate cancer. A new study from a Korean research group appears to confirm the earlier findings.
Filed under: Diagnosis, Management, Treatment | Tagged: body, localized, outcome, SBRT, stereotactic | 3 Comments »
A recent article in the Cleveland Clinic Journal of Medicine provides a summary of the way three leading specialists at this institution approach the diagnosis and management of localized prostate cancer today.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: Diagnosis, localized, Treatment | Leave a Comment »
A biopharmaceutical company called Advantagene, Inc. announced last Thursday that it has reached agreement with the U.S. Food and Drug Administration regarding the conduct of a Phase III clinical trial of a vaccine-like treatment called ProstAtak™ — in combination with standard therapy — in the treatment of patients with newly diagnosed prostate cancer.
Filed under: Drugs in development, Management | Tagged: AdV-tk, gene suicide, immunotherapy, localized, ProstAtak, vaccine, valacyclovir | Leave a Comment »
Data from a series of Japanese patients continue to help us to understand the risks and benefits of first-line treatment with high-intensity focused ultrasound (HIFU) for men initially diagnosed with localized prostate cancer and followed for up to 7 years.
Filed under: Management, Treatment | Tagged: HIFU, high-intensity focused ultrasound, localized | 2 Comments »
The abstract for the presentation of the resulsts of the REDEEM trial (to be presented on Thursday at the Gentourinary Cancer Symposium in Orlando) was published this evening on the ASCO web site. The data show that dutasteride delayed progression of prostate cancer in a well-defined group of patients compared to placebo therapy.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: dutasteride, localized, low risk, REDEEM | 9 Comments »
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