Who needs aggressive treatment after initial radiation … and who does not?

Posted on November 24, 2011 by Sitemaster

A new report in Lancet Oncology offers guidance on which patients with prostate cancer who are initially treated with radiotherapy and 6 months of neoadjuvant androgen deprivation therapy (ADT) are at relatively high and relatively low levels of risk for prostate cancer-specific mortality.

Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: , , , , , , , , , | 2 Comments »

Prostasomes — another possible marker for prostate cancer aggression?

Posted on May 12, 2011 by Sitemaster

A story in Science Daily, based on new article in the Proceedings of the National Academy of Sciences (PNAS) , has suggested that blood levels of “prostasomes” may be a more accurate marker for prostate cancer risk that PSA levels in blood.

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Inflammation, biomarkers, and risk for prostate cancer

Posted on December 23, 2010 by Sitemaster

Whether there is any real association (let alone a cause and effect correlation) between clinically evident or subclinical inflammatory disorders and risk for prostate cancer is still not known — although long suspected.

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Is free, circulating DNA a useful marker for prostate cancer?

Posted on September 28, 2010 by Sitemaster

Elevated levels of free, circulating DNA (fcDNA) have previously been been found in the serum of prostate cancer patients compared with the levels in the serum of patients with benign prostate conditions.

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Cholesterol sulfate as a potential marker for prostate cancer

Posted on August 3, 2010 by Sitemaster

In a somewhat surprising series of studies, a team of researchers at Purdue University and the Indiana University School of Medicine have demonstrated that cholesterol sulfate has high potential as a marker for prostate cancer.

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Why Ki-67 may not be USEFUL in predicting aggressive prostate cancer

Posted on April 14, 2010 by Sitemaster

A paper to be presented on Sunday at the upcoming annual meeting of the American Association for Cancer Research suggests that “the proliferative index as assessed by Ki-67 immunoreactivity is an independent predictor of aggressive prostate cancer.”

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Is the TMPRSS2-ERG marker for prostate cancer clinically relevant?

Posted on October 2, 2009 by Sitemaster

We have long cautioned about whether the presence of apparent biologic “markers” in men with prostate cancer (“association”) is necessarily an implication that a specific marker really indicates anything clinically important. A paper published by a European team now helps to put this in perspective.

Filed under: Diagnosis, Living with Prostate Cancer, Risk | Tagged: , , , , | 5 Comments »

Prostate cancer news reports: Wednesday, September 23, 2009

Posted on September 23, 2009 by Sitemaster

Today’s news reports cover items on: Extent and number of biopsy cores and eligibility for active surveillance Intermittent vs. complete androgen deprivation Hormone therapy and risk for cardiovascular disease and death Surrogate markets for disease progression in men with CRPC

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The news report: Friday, April 24, 2009

Posted on April 24, 2009 by Sitemaster

In today’s news report we touch on papers that address: Genome studies and identification of real genomic risk for prostate cancer More on the potential of 5-ARIs in prevention of prostate cancer Whether we really need more studies on selenium as a potential prostate cancer prevention agent The evolving potential of targeted focal therapy

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The Saturday prostate cancer news: November 29, 2008

Posted on November 29, 2008 by Sitemaster

We have separately addressed a report on 10-year outcome data following (non-robotic) laparoscopic radical prostatectomy for localized prostate cancer. In today’s other reports we have addressed: The potential of annexin A3 as a marker for early diagnosis of prostate cancer The ability of PSAV and PSAD to predict risk for prostate cancer in men with one or [...]

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