Delayed onset of castration resistance with serum T-based LHRH agonist regimens

A new paper just published online in Urology suggests that intermittent and testosterone (T)-based LHRH regimens are less likely to be associated with early onset of castration resistance than traditional, continuous, calender-based regimens.

Managing the side effects of bicalutamide monotherapy

In Europe, bicalutamide monotherapy with a dose of 150 mg/d is a widely used option for prostate cancer patients who wish to avoid the consequences of standard androgen deprivation using an LHRH agonist such as leuprolide acetate. However, bicalutamide induces gynecomastia (enlargement of the breasts) and mastalgia/mastodynia (pain in the breasts) in most patients.

The Wednesday news report: March 25, 2009

We have separately addressed data from a 15-year follow-up of a population-based Swedish screening study. Other reports today deal with: The impact of dietary and supplemental zinc on prostate cancer risk Prediction of risk for loss/preservation of erectile function post- prostatectomy Anti-androgen therapy and brachytherapy: options and outcomes

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