30 years follow-up of men with initially untreated, localized prostate cancer

A new article in European Urology offers interesting data on the natural history of localized prostate cancer, based on a cohort of 200+ Swedish patients followed for > 30 years. It is important to note immediately that none of these men was originally diagnosed in the PSA era. They all had some form of symptomatic disease at diagnosis. … READ MORE …

Further comment on the final results of the PIVOT study

Yesterday we suggested that we would have more to say about this study when we had read the full text of the article by Wilt et al. and the associated editorial by Thompson and Tangen. However, in all truth, others have really done this job for us, and there is little point in reinventing the wheel. … READ MORE …

Full publication of the results of the PIVOT study

The complete results of the Prostate Cancer Intervention versus Observation Trial (PIVOT) study have (finally) just been published in the New England Journal of Medicine. Unfortunately, only the abstract is available on line so it may take us a little while to get hold of a copy of the complete report. … READ MORE …

More on expectant management for screening-detected prostate cancer

Many readers may be interested in an article on active surveillance and other forms of expectant management by Khurana and Stephenson that appears on the front page of the November issue of the AUA News. This article is based on a poster presented by Khurana et al. at the annual meeting of the American Urological Association earlier this year.

Retrospective cohort analysis shows mortality benefit in prostate cancer (but there’s a big “however”)

A new report in European Urology may offer some insights into the value of large, retrospective data analyses as compared to multi-center, randomized clinical trials when it comes to the assessment of the effects of different first-line treatments on the management of clinically localized prostate cancer. … READ MORE …

The initial results of the PIVOT study

So Dr. Timothy Wilt presented the initial results of the Prostate Cancer Intervention Versus Observation Trial (PIVOT) at the annual meeting of the AUA yesterday morning. They showed what many of us may have been expecting. … READ MORE …

Follow

Get every new post delivered to your Inbox.

Join 827 other followers