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Long-term follow-up data have just been published from two studies designed to provide preliminary information on the potential use of very aggressive forms of treatment in men with high-risk categories of prostate cancer.
Filed under: Management, Treatment | Tagged: aggressive, androgen deprivation, docetaxel, hormone, paclitaxel, radiation, taxane, therapy | 7 Comments »
Today’s news reports summarize papers recently published on: Optimism, pessimism, and long-term health outcomes External beam radiation + hormone therapy for high-risk patients Quality of life and health utility after radical prostatectomy Paclitaxel + estradiol combination therapy in men progressing after docetaxel-based chemotherapy
Filed under: Management, Living with Prostate Cancer, Treatment, Drugs in development | Tagged: radical prostatectomy, quality of life, outcomes, radiation, "high risk", hormone therapy, HRQOL, paclitaxel, estradiol, optimism, pessimism | Leave a Comment »
A number of trials are currently evaluating the potential value of adjuvant chemotherapy after first-line treatment in men with high-risk prostate cancer. The effects of this form of treatment on long-term outcomes still to be established, but …
Filed under: Management, Treatment | Tagged: "high risk", adjuvant, chemotherapy, paclitaxel | Leave a Comment »
A group at the Cleveland Clinic has reported the results of a small, single-arm, Phase II trial of neoadjuvant albumin-bound paclitaxel (nab-paclitaxel or neoadjuvant Abraxane®), given prior to radical prostatectomy in high risk, locally advanced patients. Prior comparable studies with neoadjuvant docetaxel have demonstrated a PSA response but have shown no obvious antitumor activity.
Filed under: Drugs in development, Management, Treatment | Tagged: "high risk", Abraxane, locally advanced, neoadjuvant, paclitaxel | Leave a Comment »
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