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The expertise of the pathologist assessing your prostate biopsy cores may make a major difference to the way you and your doctors think you need to be treated. Indeed the following data would suggest that many prostate biopsy samples should be examined by genitourinary pathologists who really specialize in prostate pathology.
Filed under: Diagnosis, Risk | Tagged: Gleason, pattern, under-diagnosis | 2 Comments »
In recommendations made in association with a newly published study of the pathologiocal implications of “cribriform” prostate cancer tumors, Dr. Scott Lucia and colleagues are suggesting that all such tumors should be classified as Gleason grade 4 by definition.
Filed under: Diagnosis, Management, Risk | Tagged: cribriform, Gleason, pathology, pattern | 1 Comment »
We have known for a while that men with a tertiary Gleason grade of 4 or 5 (as discussed below) are at heightened risk for progressive forms of prostate cancer.
Filed under: Diagnosis, Management, Risk | Tagged: Gleason, grade, pattern, prognosis, risk, tertiary | 1 Comment »
An interesting new report from the research team at Memorial Sloan-Kettering Cancer Center has explored the relationship between the patterns of occurrence of positive lymph nodes (LNs) and the topography of the cancer in the prostate and the seminal vesicles.
Filed under: Management, Treatment | Tagged: lymph nodes, pathology, pattern, topography, tumor | Leave a Comment »
It has long been understood that men with a Gleason score (GS) of 7 could be divided into two groups: those with Gleason 4 + 3 disease (in which Gleason pattern 4 was more common or “dominant”) and those with Gleason 3 + 4 disease (in which Gleason pattern 3 was dominant).
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: biochemical, Gleason, pattern, progression, risk, score | 5 Comments »
Barocas and Penson have offered a helpful new review of racial variation in the patterns and the quality of care offered to prostate cancer patients in the USA. The entire paper is available on line through the UroToday web site.
Filed under: Living with Prostate Cancer, Management | Tagged: care, pattern, quality, race, variation | Leave a Comment »
A review by Epstein in an upcoming issue of the Journal of Urology gives a detailed perspective on the current use of the Gleason grading system, with specific emphasis on the “removal” of Gleason patterns 1 and 2 in evaluating overall Gleason scores of biopsy samples and the value of “tertiary” Gleason pattern data.
Filed under: Diagnosis, Management, Uncategorized | Tagged: Gleason, grade, modified, pattern, score, system | 6 Comments »
Burdick et al. have carried out a retrospective analysis of data from 705 patients with a pre-treatment biopsy Gleason score of 7 treated at the Cleveland Clinic between 1996 and 2005 to see if there was any difference in the outcomes of patients with a primary Gleason pattern of 3 (i.e., a Gleason score of 3 + [...]
Filed under: Management | Tagged: 3 + 4, 4 + 3, Gleason, grade, outcome, pattern | Leave a Comment »
Today’s reports address: The potential prognostic significance of a tertiary Gleason pattern in pathologic analysis of prostate cancer stage following a radical prostatectomy The relative safety of two types of external beam radiotherapy in treatment of patients with localized prostate cancer
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: cancer, Gleason, localized, news, pattern, prostate, radiotherapy, tertiary, update | Leave a Comment »
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