Low-risk prostate cancer, active surveillance, and perineural invasion

A previously unanswered question is whether a finding of perineural invasion in the biopsy cores of men who otherwise meet all relevant criteria for management by active surveillance does or does not actually increase risk for progressive forms of prostate cancer. … READ MORE …

Perineural invasion and risk for progression in localized and locally advanced disease

A new study by an Austrian research team has further helped to clarify the potential prognostic significance of perineural invasion as a risk factor in the progression of localized and locally advanced forms of prostate cancer. … READ MORE …

The prognostic significance of perineural invasion — redux

About 7 months ago we commented on an Italian study of the association between perineural invasion (PNI) on biopsy and outcomes after first-line surgical treatment for localized prostate cancer. … READ MORE …

The prognostic implications of perineural invasion at the time of surgery

A recently published Italian study has reported on whether perineural invasion (PNI) has prognostic value in patients undergoing radical prostatectomy for organ-confined prostate cancer, and on its possible correlation with other recognized prognostic factors. … READ MORE …

Prostate cancer “grows new nerves”

A press release from Baylor College of Medicine in Houston has announced that prostate cancer is associated with the development of new nerves, and that in fact the growth of such new nerves and axons may be particularly associated with aggressive forms of prostate cancer. … READ MORE …

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