114-candidate gene panel can detect nearby prostate cancer in stromal prostate tissue

There has been a lot of media “chatter” over the past 3 days about an article published in the journal Cancer Research. The article suggests that an investigational genetic test can project the presence of prostate cancer in biopsy-based specimens with an average accuracy of 97 percent.

Multi-gene profiling can lower need for prostate biopsies, but …

One of the problems with the PSA test is that it identifies a possible risk for prostate cancer in many men each year who are subsequently shown — by prostate biopsy — to be at no risk for the actual clinical condition.

Mixing genetic profiling with PSA data to project prostate cancer risk

There was a report on the AP news service yesterday which suggested that, “Scientists have taken a first step toward improving those problematic PSA tests for prostate cancer, by mixing in some genetic information that might help tell which men really need a biopsy.”

The genetics of prostate cancer risk — as seen by the WSJ

There’s an article in today’s Wall Street Journal that begins, “Scientists may soon be able to answer the agonizing question facing men with prostate cancer.” The agonizing question is whether a specific individual actually needs early and aggressive treatment for his cancer or can simply monitor it for risk of progression.

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