We really have no idea what the “best” way is to treat men with progressive disease after first-line radiation therapy.
Filed under: Uncategorized | Tagged: cryotherapy, outcome, progression, radiation, salvage | 3 Comments »
Salvage cryotherapy as second-line treatment after first-line radiation therapy
Posted on February 10, 2011 by Sitemaster
Perhaps all too much FUS about something …
Posted on February 1, 2011 by Sitemaster
As usual, some of our friends in the media are over-hyping a recent publication about the possible effects of a protein called FUS/TLS in the progression of prostate cancer.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: expression, FUS, FUS/TLS, progression, protein | Leave a Comment »
High-grade PIN and risk for clinically significant prostate cancer: an update
Posted on January 14, 2011 by Sitemaster
Work by Bostwick and his colleagues (long before the development of Bostwick Laboratories) first showed a clear association between an initial diagnosis of high-grade prostatic intraepithelial neoplasia (HG-PIN) and subsequent risk for a diagnosis of prostate cancer.
Filed under: Diagnosis, Management, Risk | Tagged: Diagnosis, HG-PIN, high-grade, outcome, prognosis, progression, prostatic intraepithelial neoplasia | 2 Comments »
Finally! Why PSA levels reflect prostate cancer progression
Posted on January 14, 2011 by Sitemaster
Although we have been using PSA to monitor the progression of prostate cancer and to test for risk of prostate cancer since the 1980s, we have never known exactly how PSA levels are associated with the increased growth of prostate cancer cells in the body.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: alpha-2 macroglobulin, α2M, progression, PSA | Leave a Comment »
The continuing importance of primary Gleason pattern 4 in Gleason 7 prostate cancer
Posted on January 6, 2011 by Sitemaster
It has long been understood that men with a Gleason score (GS) of 7 could be divided into two groups: those with Gleason 4 + 3 disease (in which Gleason pattern 4 was more common or “dominant”) and those with Gleason 3 + 4 disease (in which Gleason pattern 3 was dominant).
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: biochemical, Gleason, pattern, progression, risk, score | 5 Comments »
Does lifestyle intervention affect prostate cancer outcomes?
Posted on December 20, 2010 by Sitemaster
A new draft technology assessment report from the Agency for Healthcare Research and Quality (AHRQ) has addressed the impact of lifetyle interventions on prostate cancer (along with three other disorders).
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: intervention, lifestyle, progression, recurrence | Leave a Comment »
Initial data from Genomic Health test for recurrent or progressive prostate cancer
Posted on December 9, 2010 by Sitemaster
According to a media release this morning from Genomic Health, Inc., initial data from a large study has identified 295 genes that are strongly associated with clinical recurrence following radical prostatectomy.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: genes, localized, progression, recurrence, test | 1 Comment »
Serum T and extended survival on ADT “upgrading”
Posted on November 7, 2010 by Sitemaster
Could serum testosterone levels predict the effectiveness of combined androgen deprivation (ADT2) — through addition of an antiandrogen — in men with progressive prostate cancer and a rising PSA on LHRH agonist therapy alone?
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: ADT, ADT2, androgen deprivation therapy, outcome, progression, survival | Leave a Comment »
The genetics of prostate cancer risk — as seen by the WSJ
Posted on June 29, 2010 by Sitemaster
There’s an article in today’s Wall Street Journal that begins, “Scientists may soon be able to answer the agonizing question facing men with prostate cancer.” The agonizing question is whether a specific individual actually needs early and aggressive treatment for his cancer or can simply monitor it for risk of progression.
Filed under: Diagnosis, Management, Risk | Tagged: classification, genetics, profiling, progression, risk | 3 Comments »
The prostate cancer and statin therapy update
Posted on June 28, 2010 by Sitemaster
According to a media release from Duke Comprehensive Cancer Center, patients who take a statin after receiving a radical prostatectomy as first-line therapy for prostate cancer are at lower risk for a rising PSA after treatment than men who are not on statin therapy.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: outcome, progression, radical prostatectomy, statin | 2 Comments »
Predicting progression of low-risk patients on active surveillance
Posted on April 7, 2010 by Sitemaster
A recent article from a team at Johns Hopkins provides information about the ability to predict biopsy-based progression among their surveillance cohort of men with low-risk prostate cancer.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: active surveillance, prognosis, progression | Leave a Comment »
Prostate cancer news reports: March 17, 2010
Posted on March 17, 2010 by Sitemaster
In this news report we summarize studies dealing with: Outcomes after RP in selected patients between 70 and 81 years of age Management of men with prostate cancer recurrence after first-line EBRT Innovative MRI-guided treatments as second- and third-line forms of management Preclinical data on MAOA inhibition in prostate cancer
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: elderly, inhibitor, MAOA, progression, PSA, radical prostatectomy, recurrence | Leave a Comment »
“Unfortunately, I am that patient.”
Posted on March 10, 2010 by Sitemaster
Dr. Guy Dimonte is a specialist in fluid dynamics who works at the Los Alamos National Laboratory in New Mexico. He has recently applied the mathematical approaches used to model dynamic systems to develop a new model for the progression of prostate cancer from diagnosis onwards.
Filed under: Living with Prostate Cancer, Management, Risk | Tagged: model, prognosis, progression | 1 Comment »
The chicken or the egg … or both?
Posted on January 7, 2010 by Sitemaster
A new report has suggested that, for men already diagnosed with prostate cancer, “consumption of eggs and poultry with skin may increase the risk” of cancer recurrence or progression.
Filed under: Living with Prostate Cancer, Management | Tagged: chicken, eggs, poultry, progression, risk | 2 Comments »
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