High-risk prostate cancer: does how we define it matter?

A wide variety of clincal and pathological criteria have been proposed as data sets to stratify men into “high risk” prostate cancer groups. Nguyen et al. have now published data suggesting that the stratification criteria actually have no effect on survival (at least for six of the more commonly used criteria sets).

The early morning news: Wednesday, October 1

And hot off today’s news: A report on salvage prostatectomy in low risk patients More on the potential of active sruveillance Two “new” proteins that may affect risk and progression And some follow-up on yesterday morning’s news report

More non-ASTRO news: Wednesday, September 24

We are now able to provide a link to the abstract of the paper on diet, telomeres, and prostate cancer by Ornish et al., which we first reported on last week. Additional news today addresses: The classification of patients considered to be appropriate for active surveillance The accuracy of the Partin tables as a predictive [...]

The vagina may not “be your friend,” but …

A while ago now, in “A note on NOTES,” Dr. Krongrad reported on his learnings from a symposium and workshop on single-port laparoscopic sugical techniques (as opposed to the common multi-port approches used by most urologists to carry out radical prostatectomy today). His article was widely read.

More weekend prostate cancer news: Sunday, August 17

Additional prostate cancer news this weekend includes the following items: The role of follow-up pathology in patients with clinical stage T1a (TURP-detected) prostate cancer The impact of the number of risk factors on the likelihood of prostate cancer-specific mortality in patients with intermediate- and high-risk disease Whether a familial history of prostate cancer affects outcomes [...]

The day’s news update: Thursday, August 14

Today’s prostate cancer news update includes information related to the following areas: Long-term survival of patients with PSA levels ≥ 50 ng/mL who have been treated with radical prostatectomy The current role of bone imaging in the managment of prostate cancer The potential of targeted therapy for androgen-independent prostate cancer, based on expression of specific molecular markers

Radical prostatectomy vs. watchful waiting: an update

Bill-Axelson et al. have just published an update of the Scandinavian Prostate Cancer Research Group’s prospective, randomized trial of watchful waiting vs. radical prostatectomy. The most recent results are somewhat worrisome. For a detailed update on this study, please read the article entitled “Watchful waiting vs. radical surgery: the Scandinavian trial” elsewhere on this site. However, [...]

More prostate cancer news: Tuesday, August 12

There are several interesting new papers reported today, and two very important ones (which have been addressed in separate posts). This post addresses: A retrospective analysis of the relative predictive value of positive surgical margins following radical prostatectomy in the pre- and post-PSA eras A new nursing model for management of urinary incontinence post-prostatectomy The [...]

All the prostate cancer news for Friday, August 8

Today’s news items all focus on issues that are closely connected to the recent and controversial  guidelines issued by the US Preventive Services Task Force: The accuracy of current methods for predicting the likelihood of clinically insignificant (indolent) prostate cancer The management of patients found to have incidental prostate cancer on treatment for benign prostatic [...]

The prostate cancer news update: Tuesday, August 5

So after a few days becalmed in a world of minimal prostate cancer news … we have a fine controversy to revisit and some other interesting titbits to gnaw on …

The prostate cancer news for Thursday, July 30

News items today are focused on information about: a new way of approaching treatment of hormone-refractory disease the initial clinical trials of a new drug candidate in hormone-refractory patients the association between hospital and surgeon volume and patient outcomes after radical prostatectomy.

Prostate cancer news update, PART B: Tuesday, July 28

Here is Part B of your daily prostate cancer news update. Unless someone announces a cure for prostate cancer we will probably hold any further news until tomorrow!

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