Long-term survival of hormone-naive patients in biochemical failure post-surgery

A new paper in the European Journal of Nuclear Medicine and Molecular Imaging provides some interesting data on the long-term survival of men with progressive prostate cancer after initial treatment by radical prostatectomy. … READ MORE …

Correlating baseline PSA levels to future 10-year risk of prostate cancer diagnosis

A new paper in the Journal of Urology represents an initial attempt, based on a prospective, multi-ethnic cohort of nearly 3,000 men, to determine whether baseline PSA levels can predict, with a high level of reliability, subsequent risk for and consequential diagnosis of prostate cancer. … READ MORE …

What should one do if one’s PSA remains detectable after radical prostatectomy?

After surgery, PSA should become “undetectable” on a normal PSA test (i.e., < 0.1 ng/ml) within a month or two, but sometimes it remains elevated. The primary purpose of the ARO 96-02 randomized clinical trial was to determine whether there was an advantage to treating stage T3-4N0 patients while PSA was still undetectable, or whether they could wait to be treated. … READ MORE …

PSA levels and eligibility for active surveillance

The general rule has been that only men with low-risk prostate cancer are suitable as possible candidates for active surveillance. Low risk is defined as a PSA < 10 ng/ml; a Gleason score of ≤ 6; and a clinical stage of ≤ T2aN0M0. … READ MORE …

To screen or not to screen: an Australian “discrete choice experiment”

The question of whether men should be regularly screened for risk of prostate cancer through the use of the PSA test is (at least) controversial … READ MORE …

Prostvac-type vaccine therapy in progressive prostate cancer after first-line therapy

A study just published in European Urology has suggested that early therapy with Prostvac-type vaccines might have value in the management of men with a rising PSA after first-line therapy. … READ MORE …

PSA doubling time, seminal vesicle invasion, and efficacy of salvage radiation therapy

A small study from one hospital in Norway has suggested that PSA doubling times after surgery may predict the value of salvage radiation therapy alone as a second line form of therapy. … READ MORE …

Follow

Get every new post delivered to your Inbox.

Join 1,283 other followers