Radiation therapy may improve survival even when PSA ≥ 75 ml/ml

Sometimes, when patients originally present with very high PSA levels, a negative bone scan, and a negative CT scan, they are put on permanent androgen deprivation  therapy (ADT) because the doctor just assumes it is micrometastatic. … READ MORE …

The impact of bicycling on PSA levels … and risk for prostate cancer

Over the years it has been suggested, on and off, that bicycling may have impact on a man’s PSA levels and therefore on his potential risk for diagnosis of prostate cancer. However, there has never been any real evidence of such impact. … READ MORE …

PSA screening rates: 2005 to 2013

Numerous publications over the past 3 years have addressed the actual and potential consequences of the the US Preventive Services Task Force’s (USPSTF’s) statement discouraging the use of routine PSA-based screening for prostate cancer in otherwise healthy men. … READ MORE …

New recommendations from the AUA through “Choosing Wisely” initiative

Yesterday the American Urology Association (AUA) issued a second set of five recommendations to its members through the Choosing Wisely initiative (which is coordinated by the ABIM Foundation). Two of these recommendations were specific to risk for prostate cancer and its management. … READ MORE …

Fallout from elimination of PSA data from the SEER database

On April 29 this year, the National Cancer Institute (NCI) announced a decision to eliminate all PSA data from their current data files because of apparent inaccuracies in the ways that such data had been accumulated over time and administered. The full ramifications of this are — as yet — unclear. … READ MORE …

Long-term survival of hormone-naive patients in biochemical failure post-surgery

A new paper in the European Journal of Nuclear Medicine and Molecular Imaging provides some interesting data on the long-term survival of men with progressive prostate cancer after initial treatment by radical prostatectomy. … READ MORE …

Correlating baseline PSA levels to future 10-year risk of prostate cancer diagnosis

A new paper in the Journal of Urology represents an initial attempt, based on a prospective, multi-ethnic cohort of nearly 3,000 men, to determine whether baseline PSA levels can predict, with a high level of reliability, subsequent risk for and consequential diagnosis of prostate cancer. … READ MORE …

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