Radiation therapy for localized prostate cancer in men with diabetes mellitus

A new paper recently published on line in Urology (“the Gold Journal”) suggests that men with diabetes who are treated with curative intent for localized prostate cancer using external beam radiation therapy may experience higher than normal risk for late genitourinary complications and adverse effects. … READ MORE …

ASTRO issues new white paper on best practices for safety, effectiveness of IGRT

Image-guided methods for targeting radiation therapy (IGRT) are crucial in the treatment of localized prostate cancer. ASTRO has now issued the final version of a new white paper addressing “best practices” to improve the safety and effectiveness of these types of technology in clinical practice. … READ MORE …

Over-use of neoadjuvant and concurrent ADT in combination with radiation therapy

As anyone who has had long-term androgen deprivation therapy is well aware, this type of treatment may be able to delay the onset or relieve the metastases and bone pain associated with progressive prostate cancer, but it is far from being benign — and comes with a wide spectrum of side effects that affect some patients very seriously. … READ MORE …

EBRT + long-term ADT in treatment of men with high-risk, localized prostate cancer

A retrospective analysis has (again, somewhat predictably) shown that adding long-term androgen deprivation therapy (ADT) to dose-escalated radiation therapy improves outcomes of men initially diagnosed with high-risk prostate cancer. … READ MORE …

Anejaculation is the norm after radiation therapy to the prostate

There is a widespread misunderstanding that radiation therapy as a treatment for localized prostate cancer will allow the patient to have or recover normal ejaculatory function after treatment. Let us be very clear that this is not usually the case at all. … READ MORE …

Image guidance technology and radiation therapy for localized prostate cancer

Prostate cancer patients who are to be treated with any type of intensity-modulated radiation therapy (IMRT) for localized prostate cancer today can be pardoned if they are confused by the many ways in which that radiation therapy can be aimed and targeted through the use of image guidance (IGRT) systems. The variety of methods is significant and growing. … READ MORE …

Protons and profts: the economics that drive new medical technologies today

Luke Timmerman is a nationally respected health care journalist who specializes in writing about new healthcare technologies and writes regulary for an online business web site called Xconomy.com. Recently he took a tour of the new, $152 million ProCure proton beam radiation facility in Seattle. Click here to get his take.

Badly judged and biased political spin from the European Association for Urology

According to a media release issued by the European Association of Urology on Saturday, just prior to the opening of their annual meeting in Milan, Italy, “Surgery is superior to radiotherapy in men with localized [prostate cancer].” This headline is not even justifiable based on the content of the media release. … READ MORE …

Small study shows no long-term benefit in preventing loss of erectile function

Data from a newly-published (but very small) randomized, double-blind, placebo-controlled clinical trial show no significant, clinical impact of sildenafil (Viagra®) taken once daily as a treatment to optimize retention of erectile function at up to 2 years after radiation therapy for localized prostate cancer. … READ MORE …

More good info in the GU Cancers Symposium “Daily News”

The print and online “Daily News” provided by the organizers of the Genitourinary Cancers Symposium here in Orlando offers additional articles today that may be of interest to many InfoLink readers. … READ MORE …

18 months of ADT as good as 3 years when combined with radiation

For many years the “standard” time on treatment with androgen deprivation therapy (ADT) in combination with radiation therapy for men diagnosed with high-risk prostate cancer was 3 years, based on data from Bolla and his colleagues in Europe. This length of time on ADT has often been questioned, and a new standard may just have been set. … READ MORE …

Finally … Some long-term functional outcomes data on first-line treatment

An article in this week’s New England Journal of Medicine offers us 15-year functional outcomes data from the Prostate Cancer Outcomes Study (PCOS), which enrolled 3,533 men in whom prostate cancer was diagnosed in 1994 or 1995. … READ MORE …

Shortened penile length after radical prostatectomy: what’s new?

The fact that there is a significant degree of risk for a reduction in penile length after radical prostatectomy for the treatment of localized prostate cancer is very definitely not news (despite the fact that all too few surgeons advise their patients of such a risk). However, an accurate assessment of the probability of this risk has never been well established. … READ MORE …

No PBRT center at OHSU after careful thought

According to a pre-Christmas report in The Oregonian, Oregon Health and Science University (OHSU) has decided not to go ahead with the development of a proton beam radiation therapy (PBRT) facility. The story is also covered on MedPage Today. … READ MORE …

SBRT in men with intermediate-risk, localized prostate cancer

Data reported by Meier et al. and presented at the recent annual meeting of the American Society for Radiation Oncology (ASTRO) provide some early guidance on the efficacy and safety of sterotactic body radiation therapy (SBRT) in treatment of men with intermediate-risk, localized prostate cancer. … READ MORE …

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