radical prostatectomy « THE "NEW" PROSTATE CANCER INFOLINK

Positive surgical margins, systemic disease, and prostate cancer-specific mortality

Posted on August 27, 2011 by Sitemaster

Researchers at the Mayo Clinic have queried their large, nearly 20-year-long database of men who have undergone radical prostatectomy in an attempt to assess the correlation between positive surgical margins at the time of surgery and subsequent occurence of systemic disease or prostate cancer-specific mortality.

Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: outcome, positive surgical margins, prostate cancer-specific mortality, radical prostatectomy, systemic disease | 4 Comments »

A new way to look at side effects of first-line prostate cancer treatment

Posted on August 26, 2011 by Sitemaster

Academic research into the side effects of different treatments for localized prostate cancer have long been hampered by the lack of consistently used criteria for the assessment of those side effects at baseline and at defined time-periods post-treatment.

Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: EBRT, laparoscopic, radiation therapy, radical prostatectomy, RALP, robot-assisted, side effects, surgery | 3 Comments »

The role of radical prostatectomy in older males with high-risk prostate cancer

Posted on August 25, 2011 by Sitemaster

Data reported earlier this year from the PIVOT study and separately from the long-term Scandinavian study have shown that the surgical treatment of prostate cancer in the patients enrolled in these trials showed no median prostate-cancer specific or overall survival benefit compared to watchful waiting in patients of > 65 years of age.

Filed under: Diagnosis, Management, Risk, Treatment | Tagged: "high risk", age, elderly, old, radical prostatectomy, RALP, robot-assisted | 2 Comments »

Risk stratification of men with high-risk prostate cancer prior to first-line surgery

Posted on August 11, 2011 by Sitemaster

A new French study has attempted to provide a better appreciation of the effect of predictive factors on the biochemical recurrence-free and overall survival of patients with high-risk prostate cancer after a radical prostatectomy (RP).

Filed under: Diagnosis, Management, Risk, Treatment | Tagged: high, outcome, prediction, radical prostatectomy, risk | 4 Comments »

Long-term QoL of men in the Scandinavian Prostate Cancer Group 4 clinical trial

Posted on August 11, 2011 by Sitemaster

In 1989 the Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) started randomizing men with a clinically initiated diagnosis of localized prostate cancer to either watchful waiting or open radical prostatectomy as their primary treatment. A new paper has now addressed the long-term quality of life (QoL) of men in this study.

Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adverse effects, outcome, quality of life, radical prostatectomy, Scandinavian, SPCG-4, trial, watchful waiting | Leave a Comment »

Immediate adjuvant therapy for men with positive surgical margins after RP

Posted on August 9, 2011 by Sitemaster

There are no absolute guidelines as to which patients who have positive surgical margins after a radical prostatectomy (RP) are most appropriate for immediate adjuvant radiation therapy (with or without neoadjuvant and/or adjuvant hormone therapy).

Filed under: Management, Treatment | Tagged: adjuvant, margin, outcome, positive, radiation, radical prostatectomy | 3 Comments »

Incidence of climacturia “surprising” to one leading surgeon

Posted on August 5, 2011 by Sitemaster

It is sometimes amazing how little some physicians appear to understand about the side effects of the treatments that they give to their patients! If these were really rare side effects it might be understandable, but the one we shall discuss below is far from rare …

Filed under: Management, Treatment | Tagged: climacturia, incontinence, radical prostatectomy, sexual activity, surgery | 9 Comments »

Retrospective cohort analysis shows mortality benefit in prostate cancer (but there’s a big “however”)

Posted on July 28, 2011 by Sitemaster

A new report in European Urology may offer some insights into the value of large, retrospective data analyses as compared to multi-center, randomized clinical trials when it comes to the assessment of the effects of different first-line treatments on the management of clinically localized prostate cancer.

Filed under: Management, Treatment, Uncategorized | Tagged: age, mortality, observation, radical prostatectomy, watchful waiting | 5 Comments »

Are clinical benefits of RALP being over-hyped to unsuspecting prostate cancer patients?

Posted on July 24, 2011 by Sitemaster

Back in March, a group of authors from three major medical centers published a report in the Journal for Healthcare Quality strongly suggesting that U.S. hospitals were inappropriately over-promoting the use of robot-assisted surgery for treatment of prostate cancer.

Filed under: Management, Treatment | Tagged: hospital, outcome, promotion, radical prostatectomy, RALP, volume | Leave a Comment »

Kegel exercises, incontinence, training, and recovery of continence after RP

Posted on July 22, 2011 by Sitemaster

A new study just published in The Lancet has reported that — among men who have urinary incontinence 6 weeks after a radical prostatectomy (RP) — formal one-on-one training of patients by expert therapists does not in fact reduce the rate of continence at 12 months compared to patients in a control group.

Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: continence, exercises, incontinence, Kegel, outcome, radical prostatectomy, randomized, training, trial | 4 Comments »

Climacturia as a side effect of radical prostatectomy

Posted on July 13, 2011 by Sitemaster

“Climacturia” is the involuntary release of urine at the time of orgasm during sexual activity. A new paper by a Swedish research team has expanded our understanding of the prevalence of this problem among men after surgery for localized prostate cancer.

Filed under: Living with Prostate Cancer | Tagged: climacturia, radical prostatectomy, sexual activity | Leave a Comment »

(At least in Ontario) it’s not about where you have your surgery

Posted on July 4, 2011 by Sitemaster

Over the years, data have clearly shown that where a patient has surgical treatment for localized prostate cancer has little impact on short- and long-term outcomes (although who carries out the surgery very definitely does).

Filed under: Management, Treatment | Tagged: Ontario, outcome, positive surgical margin, PSM, radical prostatectomy | 5 Comments »

PSA monitoring after prostate cancer surgery: how long is long enough?

Posted on June 23, 2011 by Sitemaster

A paper currently “in press” in the Journal of Urology suggests that annual PSA testing “may be safely discontinued after 10 years for men with a prostatectomy Gleason score 6 or less and/or limited life expectancy.”

Filed under: Diagnosis, Management, Risk, Treatment | Tagged: follow-up, monitoring, outcomes, PSA, radical prostatectomy | 13 Comments »

A current review of the side effects of radical prostatectomy

Posted on June 21, 2011 by Sitemaster

A Swedish research team has reviewed recent published data on the side effects of radical prostatectomy. While they suggest that there have been improvements in several areas since the situation in the 1990s, they are very clear that there is still a series of significant risks associated with radical surgery as a treatment for prostate [...]

Filed under: Diagnosis, Living with Prostate Cancer, Management, Treatment | Tagged: effects, radical prostatectomy, side adverse | 2 Comments »

Age and risk for incontinence after radical prostatectomy

Posted on June 8, 2011 by Sitemaster

A new analysis of data from a large, consecutive series of Swedish patients suggests a very strong correlation between age at time of radical prostatectomy and risk for significant, long-term urinary leakage.

Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: age, education, incontinence, radical prostatectomy, risk | Leave a Comment »

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