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A new article in the Canadian Medical Association Journal has reported on a careful analysis of the published literature underlying current guidelines on the use of repetitive PSA testing to monitor risk for progression in men receiving first-line treatment for localized prostate cancer.
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: guideline, monitoring, PSA, recurrence | 3 Comments »
New data from a research team at Stanford University in California have further confirmed the effect of “heavy” smoking on the diagnosis of men with prostate cancer.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: radical prostatecomy, recurrence, smoking | 1 Comment »
The potential of high-intensity focused ultrasound (HIFU) as a form of focal therapy for treatment of cancer isolated to a portion of the prostate as opposed to treatment of the entire prostate has been recognized for a considerable period of time. However, limited data are available so far on the outcomes of men treated with [...]
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: complication, focal, HIFU, high-intensity focused ultrasound, outcome, recurrence | 5 Comments »
No currently known biomarker can accurately predict the risk of prostate cancer recurrence at the time of or immediately following first-line treatment for localized prostate cancer. The best we can currently manage is to track a patient’s PSA level and his PSA doubling time.
Filed under: Living with Prostate Cancer, Management | Tagged: miRNA, mitochondrial, prognosis, recurrence, RNA | 3 Comments »
The presence of prostate cancer in the apex (the lowest tip) of the prostate is always a challenging aspect for treatment of localized prostate cancer, because this places the cancer close to the nerves that control erectile function (potency) and to the sphincter (valve) that controls urine flow.
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: apex, HIFU, high-intensity focused ultrasound, localized, outcome, recurrence | 4 Comments »
A new retrospective analysis of data from > 2,300 patients suggests that African-American men are a greater risk for biochemical disease recurrence after brachytherapy alone than Hispanics or Caucasian men, but
Filed under: Diagnosis, Management, Risk, Treatment | Tagged: African American, brachytherapy, mortality, outcome, race, recurrence | 1 Comment »
The University of California, San Francisco (UCSF) Cancer of the Prostate Risk Assessment (CAPRA) score was initially introduced in 2005 and validated in 2006 as a pre-treatment tool that could be used to assess risk for prostate cancer recurrence after first-line treatment.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk, Treatment | Tagged: CAPRA, CAPRA-S, prognosis, recurrence, risk, surgery | 5 Comments »
New data from the Health Professionals Follow-Up Study (HPFUS) suggest that men who are smokers at the time of diagnosis of prostate cancer are at increased risk for prostate cancer progression or recurrence and prostate cancer-specific mortality compared to those who have never smoked or who stopped at least 10 years earlier.
Filed under: Diagnosis, Living with Prostate Cancer, Risk, Uncategorized | Tagged: mortality, recurrence, risk, smoking | 1 Comment »
According to a media release issued by Fox Chase Cancer Center yesterday, researchers at this institution have been able to demonstrate that “aspirin reduces the risk of cancer recurrence in some prostate cancer patients.”
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: aspirin, outcome, radiation therapy, recurrence | Leave a Comment »
A new draft technology assessment report from the Agency for Healthcare Research and Quality (AHRQ) has addressed the impact of lifetyle interventions on prostate cancer (along with three other disorders).
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: intervention, lifestyle, progression, recurrence | Leave a Comment »
According to a media release this morning from Genomic Health, Inc., initial data from a large study has identified 295 genes that are strongly associated with clinical recurrence following radical prostatectomy.
Filed under: Diagnosis, Living with Prostate Cancer, Management, Risk | Tagged: genes, localized, progression, recurrence, test | 1 Comment »
We have known since 1994 that the recurrence of some types of cancer can be driven by cancer- specific stem cells (cancerous duplicates of the normal stem cells that we all carry in our bone marrow and our blood stream). Whether this is true of all cancers is definitively not known.
Filed under: Drugs in development, Living with Prostate Cancer | Tagged: cell, recurrence, stem | Leave a Comment »
In an editorial commentary on the UroToday web site, Evans has discussed a recent paper from researchers at the University of Nijmegen on the length of positive surgical margins and the risk for prostate cancer recurrence.
Filed under: Management, Treatment | Tagged: positive surgical margin, radical prostatectomy, recurrence | 4 Comments »
Data from a small study at the University of California at San Francisco suggest that magnetic resonance (MR) spectroscopic imaging is better than T2-weighted MR imaging alone for the detection of locally recurrent prostate cancer after definitive external beam radiation therapy (EBRT) as first-line therapy.
Filed under: Management, Treatment | Tagged: detection, magentic resonance imaging, MRI, recurrence | Leave a Comment »
We know from prior studies that recurrence of prostate cancer after a radical prostatectomy is related to tumor biology and to surgical surgical skill and experience, but is one more important than the other?
Filed under: Management, Treatment | Tagged: biology, experience, outcome, recurrence, skill, surgery | 5 Comments »
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