Does surgical experience trump tumor biology (at least for patients at very high risk)?

We know from prior studies that recurrence of prostate cancer after a radical prostatectomy is related to tumor biology and to surgical surgical skill and experience, but is one more important than the other?

Prostate cancer news reports: March 17, 2010

In this news report we summarize studies dealing with: Outcomes after RP in selected patients between 70 and 81 years of age Management of men with prostate cancer recurrence after first-line EBRT Innovative MRI-guided treatments as second- and third-line forms of management Preclinical data on MAOA inhibition in prostate cancer

The data behind the $3,400 test for prostate cancer recurrence

Some days ago we commented on a media release issued by Myriad Genetics which stated that their new PROLARIS™ test “identifies patients at low risk of disease recurrence with 95% certainty.”

A new, $3,400 test for prostate cancer recurrence

Myriad Genetics has announced the launch of a 46-gene prognostic test which is supposed to be able to determine the risk of prostate cancer recurrence in patients who have undergone a radical prostatectomy.

Prostate cancer recurrence, PSADT, and patient comorbidities

D’Amico and his colleagues demonstrated some time ago that PSA velocity and PSA doubling time (PSADT) are valuable tools in predicting which patients with recurrent prostate cancer after first-line treatment are at greatest risk of metastatic disease and prostate cancer-specific mortality. But they have now shown that PSADT is less predictive of risk in men [...]

Prostate cancer news reports: Thursday, October, 2009

In today’s news reports we cover items on: Risks for prostate cancer from  smoking and increased adipose tissue The role of religious activities in prostate cancer testing among African Americans Blood loss at the time of surgery and risk for progressive disease

Prostate cancer recurrence and obesity

A new analysis of data from the Shared Equal Access Regional Cancer Hospital (SEARCH) prostate cancer database has suggested that obese men with prostate cancer are at particularly high risk for recurrence of their disease — regardless of race.

The Friday news reports (Part B): February 13, 2009

The second set of reports in today’s news commentaries encompasses new nomograms, possible new biomarkers, a specific subtype of prostate cancer, and the “hedgehog” signaling pathway.

Non-ASTRO-related news update: Thursday, September 25

Additional, non-ASTRO-related news today  includes the following: Screening, treatment, and mortality in Medicare-eligible populations Genetic variants and relationships to clinical and pathological variables The application of MRI in prostate cancer management Predictors of aggressive biochemical recurrence after radical prostatectomy

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