Neoadjuvant ADT prior to radical surgery in high-risk prostate cancer patients

A group of South Korean researchers have just reported data on the prevalence and outcomes of pT0 disease after neoadjuvant androgen deprivation therapy (ADT) and radical prostatectomy among men receiving first-line therapy for high-risk prostate cancer. … READ MORE …

Polygenicity, risk for prostate cancer, and the need for regular testing

A new study in the British Journal of Cancer suggests that knowledge of the presence of low or high numbers of known prostate cancer-related genes (polygenicity) “could” be helpful in determining which patients actually need regular testing for risk of prostate cancer. … READ MORE …

Suicide and accidental deaths among men newly diagnosed with localized prostate cancer

A new article, just accepted for publication by BJU International, has again raised the question of risk for suicide among men diagnosed with prostate cancer. … READ MORE …

Is neutrophil count a marker for risk of prostate cancer mortality?

A recent article in the journal BMC Cancer has suggested a strong association between neutrophil count and risk for overall mortality among a cohort of Canadian men treated for prostate cancer with radiation therapy ± androgen deprivation therapy (ADT). … READ MORE …

Legal risk for physicians and use/non-use of PSA testing

Dr. Gerald Chodak has raised an interesting reason why physicians may want to think hard about the U.S. Preventive Services Task Force’s recommendation on the value of PSA testing for risk of prostate cancer. … READ MORE …

Mirror, mirror, on the wall, …

For years, physicians and their patients diagnosed with low-risk prostate cancer believed that those patients were at high risk for progressive disease over time. And physicians and their patients diagnosed with a form of breast cancer known as ductal carcinoma in situ or DCIS had similar beliefs. … READ MORE …

If you have positive surgical margins post-surgery, you need to …

… know the Gleason score of the tissue at that positive surgical margin as well as and as opposed to just the Gleason score of the primary tumor. It makes a difference to your risk for biochemical recurrence. Your doctors need to know this information too! … READ MORE …

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