Tomatoes and plants and eating well to limit risk

New data just published (and associated with the ProtecT trial in the UK) has again suggested the value of tomatoes in the diet as a way to lower risk for prostate cancer — presumably because of the high levels of lycopene in tomatoes. … READ MORE …

Results of the RADAR trial at 7.4 years of follow-up

The RADAR trial (also known as TROG 03.04) was a randomized trial of 6 months of androgen deprivation therapy (ADT) + radiation therapy versus 18 months of ADT + radiotherapy, with or without additional zoledronic acid therapy, in men with intermediate- and high-risk, locally advanced prostate cancer. … READ MORE …

To quest and test (or not to quest at all)

On The New York Times‘s “Well” blog site today. Dr. Barak Gaster takes on the complex issue of how doctors need to get better at talking to patients about the pros and cons of PSA testing. And there very definitely are pros and cons! I kid you not.

Your acne’s not preventing your risk for prostate cancer

Even though we don’t remember ever coming across this suggestion before, a few studies have apparently suggested that having acne is associated with a decreased risk for a diagnosis of prostate cancer — and aggressive forms of prostate cancer in particular. … READ MORE …

Over-use of PSA testing in men > 65 with short life expectancies?

Why is it that we seem to be so focused on testing for risk of prostate cancer in older men with life expectancies of < 10 years, i.e., men who are almost certainly at very low risk for clinically significant disease? … READ MORE …

Early identification of androgen receptor gene amplification and prostate cancer risk

Historically, it has generally been assumed that androgen receptor gene amplification was a result of androgen deprivation therapy (ADT) and occurred in some 20 to 30 percent of men with castration-resistant prostate cancer (CRPC). However, … READ MORE …

Sleep disruption, melatonin levels, and risk for prostate cancer

There have been a number of studies in the past suggesting that men who work night-shifts have a higher risk for prostate cancer than those of us who work during normal “day time” hours. … READ MORE …

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