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A new article reports data from two centers on experience with whole-gland high-intensity focused ultrasound (HIFU) salvage therapy for local recurrence following external beam radiation therapy (EBRT).
Filed under: Management, Treatment | Tagged: external beam radiation therapy, HIFU, high-intensity focused ultrasound, outcome, salvage | 4 Comments »
In the October issue of European Urology there was an interesting “consensus statement” about the role of radiation therapy as adjuvant or salvage therapy for men who are at significant risk for recurrence of their prostate cancer after first-line treatment with radical prostatectomy.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: "high risk", adjuvant, post-surgery, radiation therapy, salvage | 1 Comment »
A second, small study has now offered additional data on clinical experience of the use of high-intensity focused ultrasound (HIFU) as a form of salvage therapy in men initially diagnosed with localized prostate cancer, but with a rising PSA after external beam radiation therapy (EBRT) as their first-line treatment.
Filed under: Management, Treatment | Tagged: EBRT, external beam radiation, HIFU, high-intensity focused ultrasound, salvage | 12 Comments »
Men with locally recurrent prostate cancer after first-line external beam radiation therapy (EBRT) have historically had three options for second-line treatment: salvage radical prostatectomy, salvage cryoablation, and salvage brachytherapy.
Filed under: Management, Treatment | Tagged: EBRT, external beam radiation therapy, HIFU, high-intensity focused ultrasound, QOL, quality of life, salvage | Leave a Comment »
A recent study published in “The Red Journal” suggests (perhaps not surprisingly) that radiation oncologists and urologists have different mindsets about the application of immediate adjuvant radiation therapy following surgery for prostate cancer patients with a variety of adverse pathologic risk factors.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: adjuvant, radiation, salvage, second-line | 7 Comments »
According to a media release issued last Friday, “A pelvic MRI scan with IV contrast and rectal balloon is highly effective in identifying local recurrence even at low PSA values in prostate cancer patients with a rising or persistently elevated PSA after prostatectomy.”
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: DCE, dynamic contrast-enhanced, emdorectal, MRI, radiation therapy, salvage | Leave a Comment »
An article just published on-line in Cancer has demonstrated that, in a cohort of men with a median follow-up of > 10 years, salvage radiation therapy (after first-line radical prostatectomy) reduces all-cause mortality in men with short (< 6 months) and longer (≥ 6 months) PSA doubling times at the time of initial biochemical disease progression.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: doubling time, PSA, PSADT, radiation therapy, radical prostatectomy, salvage | Comments Off
An early release paper in the Canadian Urological Association Journal offers information on a series of patients treated with external beam radiation therapy (EBRT) as salvage therapy after biochemical progression following high-intensity focused ultrasound (HIFU) as their first-line treatment.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: EBRT, external beam radiation therapy, HIFU, high-intensity focused ultrasound, salvage | Comments Off
Knowledge of the effectiveness and safety of radical prostatectomy as salvage treatment for men with biochemical recurrence after first-line radiation therapy has long been hampered by the fact that most data are based on small series of patients from individual institutions.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: outcome, radiation, radical prostatectomy, salvage, surgery | 1 Comment »
The standard form of treatment for a man with a rising PSA after a first-line radical prostatectomy (RP) is salvage radiation therapy (with or without a period of androgen deprivation). However, an Italian group has just published pilot data on the use of high-intensity focused ultrasound (HIFU) as salvage therapy after RP.
Filed under: Living with Prostate Cancer, Management, Treatment | Tagged: HIFU, pilot, radical prostatectomy, salvage | Leave a Comment »
Two recent papers from a clinical research team at the University of Western Ontario in Canada have offered us insights into the appropriate usage of cryoablation as salvage therapy for men with progressive (recurrent) prostate cancer after first-line treatment for localized and locally advanced prostate cancer.
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: cryotherapy, outcome, prognosis, salvage | Leave a Comment »
We really have no idea what the “best” way is to treat men with progressive disease after first-line radiation therapy.
Filed under: Uncategorized | Tagged: cryotherapy, outcome, progression, radiation, salvage | 3 Comments »
High-intensity focused ultrasound (HIFU) is approved in Canada for the treatment of localized prostate cancer. Since its approval, this form of treatment has become popular among patients seeking a potentially curative form of treatment with low risk for complications and side effects.
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: failure, HIFU, high-intensity focuse ultrasound, outcome, salvage, surgery | Leave a Comment »
RTOG 96-01 is a randomized, multi-center Phase III trial designed to compare bicalutamide monotherapy + salvage radiation therapy to a placebo + salvage radiation alone in men with pT2-3N0Mo prostate cancer who have an elevated PSA after surgery.
Filed under: Drugs in development, Living with Prostate Cancer, Management, Treatment | Tagged: bicalutamide, outcome, radiation, RTOG 96-01, salvage | 2 Comments »
Men with high-risk, localized prostate cancer who decide on surgery as their first-line treatment of choice are sometimes faced with the question of whether to undergo “immediate” adjuvant radiation therapy after their surgery or to do nothing and wait to see if salvage radiation therapy becomes necessary.
Filed under: Living with Prostate Cancer, Management, Treatment, Uncategorized | Tagged: adjuvant, outcome, prostatectomy, radiation, salvage | Leave a Comment »
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